Combined large-cell neuroendocrine carcinoma and atypical carcinoid of the thymus presenting as ectopic Cushing’s syndrome

Abstract

Cushing's syndrome (CS) is a well-known clinical presentation of glucocorticoid excess. However, diagnosis and treatment may still be challenging. We present a case of a young male with ectopic CS (ECS) due to combined large-cell neuroendocrine carcinoma (LCNEC) and atypical carcinoid (AC) of the thymus.