Combined high-resolution 3D CUBE T1-weighted imaging and non-contrast-enhanced magnetic resonance venography for evaluation of vein stenosis in May–Thurner syndrome

Abstract

Purpose To explore the feasibility of high-resolution MRI 3-dimensional (3D) CUBE T1-weighted magnetic resonance imaging (MRI) in combination with non-contrast-enhanced (NCE) magnetic resonance venography (MRV) for the assessment of lumen stenosis in May–Thurner syndrome. Methods Twenty-nine patients underwent computed tomography venography (CTV) and high-resolution MRI-CUBE T1, and NCE MRV acquisitions. ANOVA and LSD tests were used to compare the stenosis rate and narrowest and distal diameters of the vessel lumen. Results There were no significant differences in the estimated stenosis rate between CTV, CUBE T1, and NCE MRV (p = 0.768). However, there were significant differences in the measured stenosis diameters of the left common iliac vein (LCIV), with CTV giving the largest mean diameter and CUBE had the smallest mean diameter (p < 0.05). The measured normal LCIV diameters did not significantly differ between MRV and CUBE (p = 0.075) but were significantly larger on CTV than on MRV and CUBE (p < 0.05). Conclusions Compared with CTV, a combination of CUBE and MRV could provide an improved assessment of the degree of lumen stenosis in May–Thurner syndrome and demonstrate acute thrombosis. MRI underestimates the diameter of the vessel in comparison with CTV. MRI can be a substitute tool for Duplex ultrasound and CTV.

Application Value of a Novel Micro-Coil in High-Resolution Imaging of Experimental Mice Based on 3.0 T Clinical MR

“…In this study, the 3D CUBE sequence was used for three-dimensional imaging of mice, achieving isotropic scanning with a high spatial resolution and a high signal-to-noise ratio [28,29]. The spatial resolution was approximately 400 µm, involving volume scanning without slice spacing [30].…”