Combined hepatocellular carcinoma‐cholangiocarcinoma: Report of MR appearance in eleven patients

Campos, Rafael O.P. de; Semelka, Richard C.; Azevedo, Rafael M.; Ramalho, Miguel; Herédia, Vasco; Armao, Diane; Woosley, John T.

doi:10.1002/jmri.23754

Cited by 54 publications

(35 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meanwhile, a mixed manifestation of both tumors was not rarely seen, which is also characteristic and highly suggests cHCC-CC. Notably, the HCC-like enhancement pattern displayed with higher percentage in cirrhosis background when comparing with that in noncirrhosis background, partly concurring with de Campos et al [14] who indicated that early enhancement with partial washout on later phases seemed to be the more common enhancement pattern in cirrhotic livers. This may be related to the susceptibility of HCC generation in this specific background and would increase difficulties in differential diagnosis.…”

Section: Discussionsupporting

confidence: 76%

MR comparative study of combined hepatocellular-cholangiocarcinoma in normal, fibrotic, and cirrhotic livers

Sheng

Xie

et al. 2016

Abdom Radiol

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 76%

MR comparative study of combined hepatocellular-cholangiocarcinoma in normal, fibrotic, and cirrhotic livers

Sheng

Xie

et al. 2016

Abdom Radiol

View full text Add to dashboard Cite

show abstract

“…The evolving pathologic definition of this tumor type and the inconsistent use of radiologic terminology to describe it limits the conclusions that can be drawn. A majority of cases report rim APHE with washout appearance in the periphery (86,110,120,(124)(125)(126)(127)(128)(129)(130).…”

Section: Resultsmentioning

confidence: 99%

Evidence Supporting LI-RADS Major Features for CT- and MR Imaging–based Diagnosis of Hepatocellular Carcinoma: A Systematic Review

et al. 2018

View full text Add to dashboard Cite

The Liver Imaging Reporting and Data System (LI-RADS) standardizes the interpretation, reporting, and data collection for imaging examinations in patients at risk for hepatocellular carcinoma (HCC). It assigns category codes reflecting relative probability of HCC to imaging-detected liver observations based on major and ancillary imaging features. LI-RADS also includes imaging features suggesting malignancy other than HCC. Supported and endorsed by the American College of Radiology (ACR), the system has been developed by a committee of radiologists, hepatologists, pathologists, surgeons, lexicon experts, and ACR staff, with input from the American Association for the Study of Liver Diseases and the Organ Procurement Transplantation Network/United Network for Organ Sharing. Development of LI-RADS has been based on literature review, expert opinion, rounds of testing and iteration, and feedback from users. This article summarizes and assesses the quality of evidence supporting each LI-RADS major feature for diagnosis of HCC, as well as of the LI-RADS imaging features suggesting malignancy other than HCC. Based on the evidence, recommendations are provided for or against their continued inclusion in LI-RADS.q RSNA, 2017 Online supplemental material is available for this article.An Tang REVIEW: LI-RADS Major Features for Hepatocellular Carcinoma DiagnosisTang et al selection of five major features was based on expert opinion, the literature review was performed to ensure that imaging-based diagnostic criteria were able to achieve near-100% specificity for the noninvasive diagnosis of HCC. This review focused on the evidence supporting the inclusion of imaging features and did not attempt to gather evidence on the composition of the LI-RADS diagnostic algorithm and probability of HCC for different combinations of criteria (other than the hallmark combination of APHE and washout appearance) in the LI-RADS diagnostic table.Each subgroup was charged with developing key research questions and then critically reviewing the literature to answer research questions thematically related to its assigned topic. Search StrategyThe PICO (patient population, intervention, comparison, and outcome) format frequently used in structured reviews does not lend itself well to studies of diagnostic performance. Rather than using PICO-style questions to guide the searches, therefore, the subgroups formulated free-form questions in advance with feedback from the other subgroups. A total of 10 questions were formulated under the framework and with the understanding that their answers would inform recommendations for removing or continuing to include the corresponding LI-RADS features. After the questions were formulated, each subgroup searched the PubMed develop a standardized Liver Imaging Reporting and Data System (LI-RADS) for interpretation, reporting, and data collection of imaging studies in patients at risk for developing HCC (1). The committee was composed mainly of diagnostic radiologists, but also hepatologists, surgeons, patho...

show abstract

“…Additionally, the relative infrequency of these lesions, the evolving pathological definition, and inconsistent use of radiology terminology, provide formidable challenges to accurate analysis of the existing literature. In single‐center, retrospective case reports and series, cHCC‐CCA are described as demonstrating some form of arterial hyperenhancement (APHE), most commonly peripheral or rim‐like, on dynamic contrast‐enhanced magnetic resonance imaging (MRI) and computed tomography (CT; Table ) . Washout appearance is common and is often peripheral in location.…”

Section: Radiologymentioning

confidence: 99%

cHCC‐CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation

Brunt¹,

Aishima²,

et al. 2018

View full text Add to dashboard Cite

show abstract

Combined hepatocellular carcinoma‐cholangiocarcinoma: Report of MR appearance in eleven patients

Cited by 54 publications

References 51 publications

MR comparative study of combined hepatocellular-cholangiocarcinoma in normal, fibrotic, and cirrhotic livers

MR comparative study of combined hepatocellular-cholangiocarcinoma in normal, fibrotic, and cirrhotic livers

Evidence Supporting LI-RADS Major Features for CT- and MR Imaging–based Diagnosis of Hepatocellular Carcinoma: A Systematic Review

cHCC‐CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation

Contact Info

Product

Resources

About