Combined experimental, computational studies (synthesis, crystal structural, DFT calculations, spectral analysis) and biological evaluation of the new homonuclear complex Di-µ-benzoato-bis [benzoatodipyridine-cobalt (II)]

Synthesis, Characterisation, Hirshfeld Surface Analysis, Magnetic Susceptibility, DFT Calculations, pkCSM Profile, and Biological Activities of Novel Mono‐, Di‐, and Multinuclear Cobalt (II) Complexes

“…The results indicated that cobalt (II) complexes had the best antibacterial activity against the strains Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli compared to the other metal complexes. Similarly, in our previous work, [32] the Di-μ-benzoato-bis [ben-zoatodipyridine-cobalt (II)] complex exhibited a high antibacterial activity against six bacterial strains. Additionally, many studies have been performed on the antibacterial activity of the cobalt (II) complex of curcumin, which have shown that the cobalt (II) complex of curcumin is more active than curcumin alone.…”

“…The cobalt (II) complexes 1-3 were tested for their antimicrobial activities using the agar disk diffusion method, against five bacterial strains including two Gram-positive (Staphylococcus aureus ATCC 25923 and Streptococcus ATCC) and three Gram-negative (Escherichia coli ATCC 25922, Pseudomonas aeruginosa DMS 1117 and Klebsiella pneumoniae) as well as one fungi strain (Candida albicans ATCC 90029). [32] In 5 mL of nutrient broth, one or more colonies were dissolved until the cells in suspension reached the turbidity of the 0.5 McFarland standard. Bacterial inoculate were smeared on the surface of Muller Hinton agar using a sterile swab.…”

“…The total antioxidant capacity of Co II complexes was evaluated by the phosphomolybdenum method. [32] 100 μL of samples were combined with 900 μL of reagent solution (0.6 M sulfuric acid, 28 mM sodium phosphate, and 4 mM ammonium molybdate). The prepared tubes were incubated for 90 minutes at 95 °C.…”

Centro‐symmetric copper complex as a novel antitumor drug for therapeutic applications: Fabrication, structure, theoretical calculations, cytotoxicity, DNA binding/cleavage, and molecular docking

“…Dipole moment (μ) is a measure of polarity, charge density, and bond features in molecules. [62][63] The higher dipole moment of the Cu(AHC) 2 complex, compared with its corresponding AHC, indicates a good charge distribution of the complex. The most significant chemical parameters are HOMO (electron donor) and LUMO (electron acceptor).…”