Combined Exercise and Vitamin D on Brain-Derived Neurotrophic Factor

Abstract

Brain-derived neurotrophic factor (BDNF) is a highly conserved neurotrophic protein of the nerve growth factor family. Neurotrophins are proteins that help to stimulate and control neurogenesis, BDNF being the most active one. BDNF may be useful in the prevention and management of several diseases including Multiple Sclerosis (MS) and Diabetes. Lifestyle modifications (physical activity and diet) are among the most promising strategies for altering BDNF levels. In this chapter, we aimed to investigate the effects of aerobic and resistance training and combined exercise and vitamin D therapy on BDNF levels.