“…Furthermore, Alsace, a white wine-drinking region of France, has a much higher mortality (about 50% higher) than red wine-drinking Mediterranean areas [141], though having a lower mean serum cholesterol level [142]. In addition, several studies show cardiovascular protection induced by red wine but less by white wine [140,143,144], likely because the skins, seeds, and stems of grape are present during the fermentation of red wine but not white wine [145].…”