Combinatorial Approach of poly-D, L-lactide Encapsulated Quercetin, Piperlongumine and Curcumin Inhibits Tumour Growth in Balb/c Mice, the Colon Cancer Model
Abstract:Colon cancer has become an extreme danger to human lives due to high frequency and mortality around the world. The natural formulations based on the nanoparticles have been found promising in terms of cost, procedure and side effects. In this study, for the first time, three natural molecules- quercetin, piperlongumine and curcumin were encapsulated in biodegradable poly-D,L-lactide nanoparticles to check their anticancer potential against the colon cancer (DMH-DSS). The pure molecules, blank and loaded nanopa… Show more
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