Combinations of topical fluorides (varnishes, gels, rinses, toothpastes) versus one topical fluoride for preventing dental caries in children and adolescents

Marinho, Valéria Cc; Higgins, Jpt; Sheiham, Aubrey; Logan, Stuart

doi:10.1002/14651858.cd002781

Cited by 8 publications

(4 citation statements)

References 10 publications

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“…16,17,21,22 A review of clinical trials reported that standard fluoride toothpaste was only able to produce caries reduction (average 21%) when daily toothpaste use was complemented with fluoride gels. 62 Thus, the 6% inhibition of demineralization observed with only standard fluoride toothpaste (1450 ppm) in the present study was not unexpected. Evidence exists that high-fluoride dentifrice (5000 ppm F) is more effective in controlling root caries in elderly people than toothpaste containing either 1100 ppm or 1450 ppm F. [18][19][20] Consistent with the observations in previous studies is the appearance of a mineralized surface layer in the fluoride group in the present study (Figure 1), which is known to be associated with the presence of fluoride.…”

Section: Discussionsupporting

confidence: 62%

The Potential of Hydroxyapatite Toothpaste to Prevent Root Caries: A pH-Cycling Study

Phillips

Evans

Ugwokaegbe³

et al. 2021

CCIDE

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The effectiveness of a hydroxyapatite (HAP) toothpaste and a fluoride toothpaste in preventing root tissue demineralization (root caries) was compared using an established pH-cycling caries model. Materials and Methods: Sixty dentin blocks were produced from the root tissue of extracted human teeth and were assigned to 3 test groups (n=20/group): 10% hydroxyapatite toothpaste (HAP), 1450 ppm fluoride toothpaste (fluoride), and artificial saliva (artsaliva). Early root caries lesions were developed in each sample by 7-day demineralization using a pH-cycling caries model. The daily cyclic treatment regimen consists of two 2-minute toothpaste-slurry treatment periods, one 6-hour acid challenge using acidified gel (pH 4.5), and then storage in remineralizing solution (artsaliva) for the rest of the time. Demineralization was assessed as the amount of mineral loss (∆z) using transverse microradiography (TMR). Pairwise comparisons (between treatments) were performed using analysis of variance (ANOVA), and then Tukey's HSD for multiple comparisons. All p-values are considered significant if p<0.05. Results: Both ANOVA and Tukey's HSD indicated no significant (ANOVA; n=20) difference in mean ∆z among the groups, with least ∆z (±Sd) in the HAP (1117±366) compared to fluoride (1392±334) and artsaliva (1406±223). Relative to control, HAP and fluoride inhibited root demineralization by 21% and 6%, respectively. Conclusion: Within the limit of the present study, the tested toothpaste containing 10% HAP is an effective root caries control toothpaste. Toothpaste containing 10% HAP was slightly more effective in preventing tooth demineralization than 1450 ppm fluoride provided as sodium fluoride. Thus, this study shows that HAP toothpastes can serve as an effective alternative to fluoride toothpastes for root caries management.

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Section: Discussionsupporting

confidence: 62%

The Potential of Hydroxyapatite Toothpaste to Prevent Root Caries: A pH-Cycling Study

Phillips

Evans

Ugwokaegbe³

et al. 2021

CCIDE

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“…The use of luoride in various methods such as water luoridation, toothpaste, sealants, mouth rinses, professional topical agents is considered a measure of great importance for the prevention of dental caries, owing to the anti-cariogenic property of dental caries (Marinho, 2004;Marinho V. C. C., 2015;Lavanya Govindaraju., Ganesh Jeevanandan., E. M. G. Subramanian, 2017). Fluoride varnishes have been described as the most convenient form of professional use of topical luoride in preschool children, based on the premise that they are easy to apply and well-tolerated (L Govindaraju., .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of parents willingness to take up fluoride treatment for their children, the gender differences and common age of acceptance - A retrospective study

Ramya

Ravindran

Jeevitha

2020

ijrps

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Fluoride used as a chemotherapeutic agent for caries prevention has been widely researched and documented. The change in the prevalence of caries and advent of different fluoride formulations along with the desire to maximize the benefits and minimise the side effects has led to evoking guidelines for its use. Fluoride varnish, which is one of the most important materials to prevent early childhood caries, is easy to apply and well-tolerated by children. The study aims in assessing the perception of parents towards professional fluoride treatment, opinions, differences and evaluating the prevalent condition. The study was performed in the outpatient department of Pediatric and Preventive Dentistry. Data required for the study was procured by reviewing patient records and analysed data of 86000 patients between June 2019 to March 2020. The data was sorted in excel and statistically analysed using the IBM SPSS software analysis and the results interpreted in graphs and tabulations. The prevalence of fluoride treatment was found to be 37.7%. The study shows a female predilection (Chi-square test; p-value- 0.252) and age is found to be negatively correlating with fluoride type (p<0.01). It is imperative that regular professional fluoride treatment for pediatric patients is followed by parents to prevent and manage tooth decay effectively.

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“…during the period of eruption of first permanent molars [16]. Even though the literature indicates that any fluoride application over a period of 2–3 years, be it a varnish, a fluoride gel or fluoride rinse results only in a modest additional caries preventive effect of about 10% when used together with daily toothbrushing with fluoride toothpaste [17], SDF applications were not included in this systematic review. One study has shown promising results with SDF on caries prevention [18], while a systematic review concluded that SDF was more effective than fluoride varnish in preventing caries [19].…”

Section: Introductionmentioning

confidence: 99%

Caries preventive efficacy of silver diammine fluoride (SDF) and ART sealants in a school-based daily fluoride toothbrushing program in the Philippines

et al. 2012

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BackgroundOcclusal surfaces of erupting and newly erupted permanent molars are particularly susceptible to caries.The objective of the study was to assess and compare the effect of a single application of 38% SDF with ART sealants and no treatment in preventing dentinal (D3) caries lesions on occlusal surfaces of permanent first molars of school children who participated in a daily school-based toothbrushing program with fluoride toothpaste.MethodsThe prospective community clinical trial in the Philippines was conducted over a period of 18 months and included 704 six- to eight-year-old school children in eight public elementary schools with a daily school-based fluoride toothpaste brushing program. Children were randomly assigned for SDF application or ART sealant treatment. Children from two of the eight schools did not receive SDF or ART sealant treatment and served as controls. SDF or ART sealant treatment was applied on sound occlusal surfaces of permanent first molars. Surfaces that were originally defined as sound at baseline but which changed to dentinal (D3) caries lesions were defined as surfaces with new caries (caries increment). Non-compliance to the daily toothbrushing program in three schools offered the opportunity to analyze the caries preventive effect of SDF and sealants separately in fluoride toothpaste brushing and in non-toothbrushing children.ResultsIn the brushing group, caries increment in the SDF treatment group was comparable with the non-treatment group but caries increment in the sealant group was lower than in the non-treatment group with a statistically significant lower hazard ratio of 0.12 (0.02-0.61). In the non-brushing group, caries increment in the SDF treatment group and the sealant group was lower than the non-treatment group but the hazard ratio was only statistically significant for the sealant group (HR 0.33; 0.20-0.54). Caries increment was lower in toothbrushing children than in non-toothbrushing children. Hazard ratios reached statistical significance for the non-treated children (HR 0.43; 0.21-0.87) and the sealant-treated children (HR 0.15; 0.03-0.072).ConclusionsA one-time application of 38% SDF on the occlusal surfaces of permanent first molars of six- to eight-year-old children is not an effective method to prevent dentinal (D3) caries lesions. ART sealants significantly reduced the onset of caries over a period of 18 months.Trial registration numberGerman Clinical Trial Register DRKS00003427

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Combinations of topical fluorides (varnishes, gels, rinses, toothpastes) versus one topical fluoride for preventing dental caries in children and adolescents

Cited by 8 publications

References 10 publications

The Potential of Hydroxyapatite Toothpaste to Prevent Root Caries: A pH-Cycling Study

The Potential of Hydroxyapatite Toothpaste to Prevent Root Caries: A pH-Cycling Study

Prevalence of parents willingness to take up fluoride treatment for their children, the gender differences and common age of acceptance - A retrospective study

Caries preventive efficacy of silver diammine fluoride (SDF) and ART sealants in a school-based daily fluoride toothbrushing program in the Philippines

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