Combination Treatment of Low-Fluence 1,064-nm Q-Switched Nd

Yun, Woo Jin; Moon, Hye-Rim; Lee, Mi-Woo; Choi, Jee‐Ho; Chang, Sung‐Eun

doi:10.1097/dss.0000000000000057

Cited by 43 publications

(23 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The number of required treatments is generally more than those for other light- and laser-based treatment modalities. Several recent studies suggest that fractionating the laser energy (Yue et al, 2016) or combining low-fluence Q-switched lasers with long-pulsed Nd:YAG (laser toning [Kang et al, 2011] or IPL [Vachiramon et al, 2015, Yun et al, 2014]) may reduce the recurrence rate. However, until the recurrence rate is reduced significantly in a reproducible way and the relatively high rates of posttreatment dyspigmentation are resolved, Q-switched laser therapy for patients with melasma is likely reserved for very recalcitrant cases that have failed with other laser modalities first.…”

Section: Overview Of Laser- and Light-based Treatment Optionsmentioning

confidence: 99%

A review of laser and light therapy in melasma

Trivedi

Yang

Cho³

2017

International Journal of Women's Dermatology

129

135

View full text Add to dashboard Cite

Melasma is a dysregulation of the homeostatic mechanisms that control skin pigmentation and excess pigment is produced. Traditional treatment approaches with topical medications and chemical peels are commonly used but due to the refractory and recurrent nature of melasma, patients often seek alternative treatment strategies such as laser and light therapy. Several types of laser and light therapy have been studied in the treatment of melasma. Intense pulsed light, low fluence Q-switched lasers, and non-ablative fractionated lasers are the most common lasers and light treatments that are currently performed. They all appear effective but there is a high level of recurrence with time and some techniques are associated with an increased risk for postinflammatory hyper- or hypopigmentation. The number and frequency of treatments varies by device type but overall, Q-switched lasers require the greatest number of treatment applications to see a benefit. Vascular-specific lasers do not appear to be effective for the treatment of melasma. Ablative fractionated lasers should be used with caution because they have a very high risk for postinflammatory hypo- and hyperpigmentation. The use of nonablative fractionated laser treatments compared with other laser and light options may result in slightly longer remission intervals. Picosecond lasers, fractional radiofrequency, and laser-assisted drug delivery are promising future approaches to treat melasma. The goal of this review is to summarize the efficacy and safety of the most commonly used laser and light therapies to treat melasma, briefly present future laser-based treatment options for patients with melasma, and provide recommendations for treatment on the basis of the reviewed information.

show abstract

Section: Overview Of Laser- and Light-based Treatment Optionsmentioning

confidence: 99%

A review of laser and light therapy in melasma

Trivedi

Yang

Cho³

2017

International Journal of Women's Dermatology

129

135

View full text Add to dashboard Cite

show abstract

“…Another article has been excluded because this has been retracted from PubMed. [ 84 ] Finally, 10 studies evaluated LFQS Nd:YAG laser on 446 patients[ 85 86 87 88 89 90 91 92 93 94 ] [ Table 11 ].…”

Section: Chemical Peelsmentioning

confidence: 99%

Evidence-based review, grade of recommendation, and suggested treatment recommendations for melasma

Sarma

Chakraborty

Poojary

et al. 2017

Indian Dermatol Online J

View full text Add to dashboard Cite

Treatment of melasma is known to be less satisfactory, often incomplete, and relapse is frequent. Although many treatment options are available, they are either known to be unsafe on long-term use or their long-term safety profile is unknown. Patients often use various drugs, even topical steroid-based preparation without any medical supervision for long period of time, making the skin unsuitable for many of the drugs available. Thus, there has been gross disparity among the treating physician about what drugs and what regimen are best suitable for various categories of melasma patients and in different situations. With this background, numerous newer drugs, mostly combinations of some proprietary molecules or even unknown plant extracts, have flooded the market for the management of melasma. Information on efficacy or safety of these products are almost unknown. Studies on Asian people, especially Indian population, are far less commonly available. Therapeutic guideline for use on Indian patients with melasma is almost missing. Extrapolation of data from Caucasian people for use on Asian people may not be scientifically justifiable because Caucasian and Asian people are known to have inherent difference in their response as well as tolerance to the drugs used for melasma. With this background, we have extensively evaluated, following a strict, scientifically designed protocol, all the available studies on melasma management till May 2016 and prepared this document on level of evidence, grade of recommendation and suggested therapeutic guideline for melasma as per the method proposed by Oxford Centre of Evidence-Based Medicine. Various ethical, social, logical, regional, and economic issues in the context of Indian and similar populations were given due importance while preparing the suggested therapeutic recommendation.

show abstract

“…One study treated 12 patients with fractionated IPL (IPL-F) and low-fluence (LF) QS-1,064 nm Nd:YAG laser therapy and compared the MASI scores to those of 12 patients who underwent the same number of treatments with IPL-F alone. This study found a greater improvement in the combination treatment group than those who were treated with IPL-F alone ( Yun et al, 2014 ). Combination CO 2 laser therapy in combination with QS-alexandrite (alex) laser therapy showed better results than therapy with QS-alex alone but was associated with more frequent adverse effects ( Angsuwarangsee and Polnikorn, 2003 ).…”

Section: Melasmamentioning

confidence: 72%

Laser treatment of medical skin disease in women

LaRosa

Chiaravalloti

Jinna

et al. 2017

International Journal of Women's Dermatology

View full text Add to dashboard Cite

Laser treatment is a relatively new and increasingly popular modality for the treatment of many dermatologic conditions. A number of conditions that predominantly occur in women and that have a paucity of effective treatments include rosacea, connective tissue disease, melasma, nevus of Ota, lichen sclerosus (LS), notalgia paresthetica and macular amyloidosis, and syringomas. Laser therapy is an important option for the treatment of patients with these conditions. This article will review the body of literature that exists for the laser treatment of women with these medical conditions.

show abstract

Combination Treatment of Low-Fluence 1,064-nm Q-Switched Nd

Abstract: Our results suggest that the combination of the IPL-F with LF-QS-Nd:YAG laser may be an effective and safe modality for melasma patients.

Cited by 43 publications

References 22 publications

A review of laser and light therapy in melasma

A review of laser and light therapy in melasma

Evidence-based review, grade of recommendation, and suggested treatment recommendations for melasma

Laser treatment of medical skin disease in women

Contact Info

Product

Resources

About