Combination therapy of scalp electro-acupuncture and medication for the treatment of Parkinson's disease: A systematic review and meta-analysis

Qiang, Tianyao; Gai, Cong; Chai, Yuan; Feng, Wandi; Ma, Haojie; Zhang, Yi; Feng, Jing; Guo, Zhenyu; Ma, Liang; Sun, Haixiang

doi:10.1016/j.jtcms.2019.01.005

Cited by 4 publications

(5 citation statements)

References 31 publications

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“…The characteristics of the 11 SRs/MAs included in our final analysis are summarized in Table 2 . They were published between 2010 and 2019, and 9 of them were published since 2015 ( 39 – 43 , 45 – 48 ). The number of primary studies included in each review ranged from 8 to 42, and the sample sizes ranged from 474 to 2,625.…”

Section: Resultsmentioning

confidence: 99%

“…A total of seven reviews ( 40 , 42 , 43 , 45 , 46 , 48 , 49 ) analyzed the effective rate of acupuncture for PD. In six reviews ( 40 , 42 , 43 , 45 , 46 , 48 ) that used effective rate to compare the effects of acupuncture plus madopar treatment vs. madopar treatment alone, the combined treatment had a significantly greater effect on PD symptoms. Two reviews ( 48 , 49 ) used effective rate to compare the effects of acupuncture vs. madopar treatment alone.…”

Section: Discussionmentioning

confidence: 99%

“…Six reviews ( 39 – 41 , 44 , 45 , 48 ) used the Webster Scale to compare the effects of acupuncture plus madopar vs. madopar alone and found that the combined treatment had a greater effect than madopar alone. In two reviews ( 41 , 48 ) that used the Webster Scale to compare the effects of acupuncture vs. madopar, a significant effect of acupuncture on PD symptoms was observed [WMD = −2.50.…”

Section: Discussionmentioning

confidence: 99%

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Effectiveness of Acupuncture in the Treatment of Parkinson's Disease: An Overview of Systematic Reviews

et al. 2020

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Background: The effects of acupuncture on Parkinson's disease (PD) outcomes remain unclear. The aim of this overview was to comprehensively evaluate the methodological quality and applicability of the results of systematic reviews (SRs)/meta-analyses (MAs) that examined the use of acupuncture to treat PD. Methods: Eight databases were searched to retrieve SRs/MAs on the use of acupuncture for the treatment of PD. Two reviewers independently screened and extracted the data using the Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2) checklist to evaluate the methodological quality and using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) criteria to assess the evidence quality of the included reviews. Results: A total of 11 SRs/MAs were included. According to the AMSTAR-2 checklist results, all included SRs/MAs were rated as very-low-quality studies. The GRADE criteria revealed 20 studies with very-low-quality evidence, 9 with low-quality evidence, 3 with moderate-quality evidence, and 0 with high-quality evidence. Descriptive analysis showed that acupuncture appears to be a clinically effective and safe treatment for PD. Conclusions: The use of acupuncture for the treatment of PD may be clinically effective and safe. This conclusion must be interpreted cautiously due to the generally low methodological quality and low quality of evidence of the included studies.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Effectiveness of Acupuncture in the Treatment of Parkinson's Disease: An Overview of Systematic Reviews

et al. 2020

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“…Comprehensive evidence for the efficacy and safety of acupuncture in PD has been provided by a total of twelve systematic reviews (SRs) or meta-analyses (MAs) assessing this topic, involving 179 randomized controlled trials (RCTs) with a total of 11,717 participants [12]. These SRs/MAs have compared the effects of acupuncture combined with medication versus medication alone, demonstrating better efficacy at symptom alleviation with the combination of acupuncture with medication compared to medication alone [13]. The Unified Parkinson's Disease Rating Scale (UPDRS) provides a comprehensive, efficient, and flexible means of monitoring PD-related disabilities and impairments as well as treatment evaluation, assessing behavior and mood, activities of daily living, motor functions, and therapeutic complications [14].…”

Section: Clinical Efficacy Of Acupuncture In Parkinson's Disease Patientsmentioning

confidence: 99%

Acupuncture for Parkinson’s Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit

et al. 2021

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Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disease caused by degeneration of dopaminergic neurons in the substantia nigra. Existing pharmaceutical treatments offer alleviation of symptoms but cannot delay disease progression and are often associated with significant side effects. Clinical studies have demonstrated that acupuncture may be beneficial for PD treatment, particularly in terms of ameliorating PD symptoms when combined with anti-PD medication, reducing the required dose of medication and associated side effects. During early stages of PD, acupuncture may even be used to replace medication. It has also been found that acupuncture can protect dopaminergic neurons from degeneration via antioxidative stress, anti-inflammatory, and antiapoptotic pathways as well as modulating the neurotransmitter balance in the basal ganglia circuit. Here, we review current studies and reflect on the potential of acupuncture as a novel and effective treatment strategy for PD. We found that particularly during the early stages, acupuncture may reduce neurodegeneration of dopaminergic neurons and regulate the balance of the dopaminergic circuit, thus delaying the progression of the disease. The benefits of acupuncture will need to be further verified through basic and clinical studies.

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“…They proposed that the establishment of standardized treatment methods is essential for improving the quality of SA studies. Qiang et al, You et al, and Zhang et al [19][20][21][22] concluded that the unification of SA points and the standardization of SA treatment methods and protocols are needed for clinical trials to effectively inform clinical practice.…”

Section: Introductionmentioning

confidence: 99%

Anatomical and Clinical Characteristics of Scalp Acupuncture Systems: a Scoping Review and Synthesis

Wise,

Lorenc

2023

J Acupunct Meridian Stud

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Scalp acupuncture is a therapeutic procedure that involves inserting needles into the scalp to treat various medical conditions, including pain and neurological and psychological disorders. The inter-system variability of scalp acupuncture limits secondary analysis and evidence synthesis, delaying its inclusion into evidence-based healthcare policies and establishment as a treatment intervention recognized by Western medicine. This scoping review aimed to identify the range of scalp acupuncture systems, systematically collect and summarize information on their general, anatomical, and clinical characteristics, and build a framework for understanding scalp acupuncture systems. This review included all English-language publications on scalp acupuncture applied to treat any health condition in humans. Extensive searches were conducted across bibliographic databases, journals, trial registries, and supplementary sources. The detailed general, anatomical, and clinical application characteristics of 19 scalp acupuncture systems were extracted. Data were collected and analyzed using charting and image manipulation software. Framework synthesis was performed using the Standard International Acupuncture Nomenclature Scalp Acupuncture as an a priori framework. The review revealed that the heterogeneity related to scalp acupuncture methods can be attributed to the high variability among the theoretical bases of different systems, intersystem mismatch in anatomical locations of treatment points and areas on the scalp, and inconsistencies in the methods used for locating them. These discrepancies in anatomical and clinical features have limited the synthesis and development of a framework for scalp acupuncture. Discussion and agreement on the anatomical locations of scalp stimulation areas, identification of methods for precise positioning of acupuncture areas on the scalp, and further exploration of theoretical bases will aid in the standardization of scalp acupuncture and improve the quality of research in this area.

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Combination therapy of scalp electro-acupuncture and medication for the treatment of Parkinson's disease: A systematic review and meta-analysis

Cited by 4 publications

References 31 publications

Effectiveness of Acupuncture in the Treatment of Parkinson's Disease: An Overview of Systematic Reviews

Effectiveness of Acupuncture in the Treatment of Parkinson's Disease: An Overview of Systematic Reviews

Acupuncture for Parkinson’s Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit

Anatomical and Clinical Characteristics of Scalp Acupuncture Systems: a Scoping Review and Synthesis

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