Combination Therapy: Complexing of QDs with Tetrapyrrols and Other Dyes

Маслов, В. Г.; Орлова, А. О.; Баранов, А. В.

doi:10.1007/978-90-481-3872-2_7

Cited by 9 publications

(17 citation statements)

References 68 publications

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“…red shift of the lowest energy absorption band to ~ 662 nm. According to [8], these changes in the Ce6 absorption spectrum indicate formation of the QD/Ce6 complexes. No traces of the unbounded Ce6 were found in the absorption spectra of both mixed solutions.…”

Section: Complexes Formationmentioning

confidence: 98%

“…It should be pointed out that Ce6 at pH 6 is in dimeric form [8]. After binding to the QD surface, Ce6 molecules disaggregate to the monomers [16].…”

Section: Energy Transfer In Qd/ce6 Complexesmentioning

confidence: 98%

“…Analysis of this dependence provides information about stoichiometry of the QD/Ce6 complexes, as well as about the physical mechanism of PL quenching of nanocrystals [8]. Dependence of the relative intensity of the QD PL, I/I0 on the molar ratio of the components in the mixture (n = CCe6/CQDs) is shown in Figure 3.…”

Section: Pl Properties Of Qd/ce6 Complexesmentioning

confidence: 99%

“…As a rule, dependence of the QD PL intensity on acceptor concentration in such systems is described by an exponential function, since the distribution of acceptors on the QD surface is determined by statistical Poisson distribution [8]. Analysis of this dependence provides information about stoichiometry of the QD/Ce6 complexes, as well as about the physical mechanism of PL quenching of nanocrystals [8].…”

Section: Pl Properties Of Qd/ce6 Complexesmentioning

confidence: 99%

“…Quantum dots containing cadmium ions are the traditional donors used in such complexes [8]. The presence of cadmium in the QD composition is a serious argument against using these complexes in biological and medical applications.…”

Section: Introductionmentioning

confidence: 99%

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Energy transfer efficiency in quantum dot/chlorin e6 complexes

et al. 2015

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New biocompatible complexes based on manganese-doped core/shell ZnS/ZnS quantum dots (ZnS:Mn 2+ /ZnS) and drug "Photoditazin" were formed and compared to traditional complexes with CdSe/ZnS quantum dots. Complexes with ZnS:Mn/ZnS quantum dots show some advantages in their photophysical properties. At the same time they demonstrate evident difference in their photophysical properties that may be associated with various location of trap states in places where drug molecule bounds with quantum dot.

show abstract

Section: Complexes Formationmentioning

confidence: 98%

“…It should be pointed out that Ce6 at pH 6 is in dimeric form [8]. After binding to the QD surface, Ce6 molecules disaggregate to the monomers [16].…”

Section: Energy Transfer In Qd/ce6 Complexesmentioning

confidence: 98%

Section: Pl Properties Of Qd/ce6 Complexesmentioning

confidence: 99%

Section: Pl Properties Of Qd/ce6 Complexesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Energy transfer efficiency in quantum dot/chlorin e6 complexes

et al. 2015

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Investigation of Complexes of CdTe Quantum Dots with the AlOH-Sulphophthalocyanine Molecules in Aqueous Media

et al. 2013

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The interaction between negatively charged CdTe quantum dots and AlOH-sulphophthalocyanine molecules in blood plasma and in aqueous solutions with different pH levels has been investigated. Similarly charged quantum dots and molecules are found to form complexes that exhibit an effective energy transfer. The efficiency of the energy transfer in these complexes is close to the theoretical FRET efficiency for a given donor−acceptor pair. It has been shown that in blood plasma, as well as in aqueous solutions, the formation of complexes of quantum dots with AlOH-sulphophthalocyanine molecules without using their charged groups allows preserving the photophysical properties of phthalocyanine molecules. A theoretical model of the formation of complexes between similarly charged quantum dots and molecules is proposed.

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Chlorin e6–ZnSe/ZnS quantum dots based system as reagent for photodynamic therapy

et al. 2015

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Stable water-soluble complexes of Cd-free ZnSe/ZnS quantum dots (QDs) and chlorin e6 complexes have been prepared. These complexes have shown approximately 50% intracomplex fluorescence resonance energy transfer from QDs to chlorin e6. The photodynamic therapy (PDT) test of the complexes against the Erlich acsite carcinoma cell culture demonstrated a two-fold enhancement of the cancer cell photodynamic destruction as compared to that of free chlorin e6 molecules. It was shown that the PDT effect was significantly increased due to two factors: the efficient QD-chlorin e6 photoexcitation energy transfer and the improvement of cellular uptake of the photosensitizer in the presence of ZnSe/ZnS QDs.

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Combination Therapy: Complexing of QDs with Tetrapyrrols and Other Dyes

Cited by 9 publications

References 68 publications

Energy transfer efficiency in quantum dot/chlorin e6 complexes

Energy transfer efficiency in quantum dot/chlorin e6 complexes

Investigation of Complexes of CdTe Quantum Dots with the AlOH-Sulphophthalocyanine Molecules in Aqueous Media

Chlorin e6–ZnSe/ZnS quantum dots based system as reagent for photodynamic therapy

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