Combination of qualitative and quantitative methods for developing a new Health Related Quality of Life measure for patients with anogenital warts

Badı́a, Xavier; Colombo, José A; Lara, Núria; Llorens, M.A.; Olmos, L.; Terreros, Miguel Sainz de los; Varela, J. A.; Vilata, J.J.

doi:10.1186/1477-7525-3-24

Cited by 35 publications

(31 citation statements)

References 16 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Overall, our data coincide with several studies indicating that most men are unaware that GW are caused by HPV infection [13], [30], [32]–[33]. Although some reports have documented the negative impact of GW on individuals’ quality of life, sexuality and psychological status [12], [16]–[19], [34]–[38], few qualitative studies have employed in-depth approaches to understand the experiences of men with GW [12], [15], [18]–[19], [34], [36], and none have obtained the particular views of South American transgendered women, sex workers or people without GW on this health problem, although a high HPV prevalence has been found in these groups in Argentina, Brazil and Peru [4]–[5], [39].…”

Section: Discussionsupporting

confidence: 90%

HPV and Genital Warts among Peruvian Men Who Have Sex with Men and Transgender People: Knowledge, Attitudes and Treatment Experiences

Nureña

Brown

Galea³

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

BackgroundSeveral studies have assessed the epidemiology of HPV infection among MSM, but no qualitative studies have specifically assessed how HPV and genital warts (GW) affect South American men who have sex with men (MSM) and male-to-female transgendered women (TG). This study explored the knowledge, attitudes and experiences of Peruvian MSM and TG regarding HPV and GW.MethodsWe performed a qualitative study consisting of fifteen in-depth interviews and three focus groups carried out in Lima, Peru with diverse MSM and TG groups, including sex workers. Resulting data were analyzed by applying a systematic comparative and descriptive content analysis.ResultsWhile knowledge of HPV was limited, awareness of GW was common, particularly among TG persons and sex workers. Still, few participants recognized that GW are sexually transmitted, and many had problems differentiating between GW and other STI/anogenital conditions. Stigmatizing experiences were common during sexual encounters with people who had visible GW. Shame, emotional and physical troubles, and embarrassing sexual experiences were reported by individuals with GW. Search for treatment was mediated by peers, but stigma and apparent health services’ inability to deal with GW limited the access to effective medical care.ConclusionsIn Peru, public health interventions should strengthen services for HPV/GW management and increase accurate knowledge of the transmission, treatment, and sequelae of HPV/GW in MSM and TG populations.

show abstract

Section: Discussionsupporting

confidence: 90%

HPV and Genital Warts among Peruvian Men Who Have Sex with Men and Transgender People: Knowledge, Attitudes and Treatment Experiences

Nureña

Brown

Galea³

et al. 2013

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…The results of other studies have suggested that this association can greatly influence the perception of illness; conversely, women may regard cervical dysplasia as stigmatising when they are informed about the sexual transmission of HPV [4,32]. …”

Section: Discussionmentioning

confidence: 99%

The quality of life of patients with genital warts: a qualitative study

Mortensen¹,

Larsen

2010

BMC Public Health

View full text Add to dashboard Cite

BackgroundGenital warts, which are caused by infection with human papillomavirus (HPV), are one of the most common sexually transmitted diseases in Europe. Although genital warts are commonly perceived as a non-serious condition, treatment is often long, of varying effectiveness and the recurrence rate is high. Very few studies have been performed on the personal consequences of genital warts. The aim of this qualitative study, set in Denmark, was to examine the ways in which genital warts may affect patients' quality of life.MethodsTo obtain an in-depth understanding of patients' perceptions of genital warts, we used qualitative focus-group interviews with five men and five women aged between 18 and 30 years who had genital warts. The interview guide was based on a literature review that identified important issues and questions. The data were analysed using a medical anthropological approach.ResultsPatients' experiences were related to cultural conceptions of venereal diseases and the respective identities and sexuality of the sexes. The disease had negative psychological and social effects both for men and for women and it affected their sex and love lives, in particular. The psychological burden of the disease was increased by the uncertain timeline and the varying effectiveness of treatment. We identified a need for more patient information about the disease and its psycho-sexual aspects.ConclusionsThe men and women participating in this study considered their quality of life to be significantly lowered because of genital warts. The experiences described by the participants give insights that may be valuable in treatment and counselling.The quadrivalent HPV vaccine that has now been added to the childhood vaccination programme for girls in Denmark for the prevention of cervical cancer can also prevent 90% of cases of genital warts. Our results suggest that HPV vaccination could considerably reduce the largely unacknowledged psychological and social burden associated with genital warts, in men as well as women.

show abstract

“…The prescribed medication was recorded in patients included in the sensitivity group. The CECA questionnaire and the Spanish validated version of the Dermatology Life Quality Index (DLQI) (12,14) were administered at the same time each visit. During the follow-up visit, at 10 ± 3 weeks from baseline for patients in the sensitivity group, and at 15 days from baseline for patients in the reliability group, clinical characteristics were evaluated and the CECA and DLQI questionnaires were again administered, in addition to changes in a single item of self-perceived health status with reference to baseline.…”

Section: Validation and Clinical Use Of The Ceca A Disease-specific mentioning

confidence: 99%

“…The higher the score, the more quality of life is impaired. The DLQI has been translated and validated for use in the Spanish population (12,14).…”

Section: Validation and Clinical Use Of The Ceca A Disease-specific mentioning

confidence: 99%

“…The increasing interest in measures reflecting the personal viewpoint of patients' health has led to an extended demand for reliable and valid standardized questionnaires of health-related quality of life (HRQL) (11). Disease-specific questionnaires, those that only contain items specifically designed for a particular condition, are more likely to be relevant and sensitive to patients in areas that clinicians may wish to monitor (12). In patients with genital condylomata acuminata, a specific HRQL questionnaire, called CECA (Cuestionario Específico para Condiloma Acuminado), has been developed with the objective of being used in clinical research and clinical practice.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Validation and Clinical Use of the CECA, a Disease-specific Quality of Life Questionnaire for Patients with Anogenital Condylomata Acuminata

Vilata

Varela²,

Olmos³

et al. 2020

Acta Derm Venerol

View full text Add to dashboard Cite

The aim of this validation study was to assess the measurement properties of the CECA (Spanish acronym for the Specific Questionnaire for Condylomata Acuminata) in patients with anogenital condylomas. A total of 247 patients aged > 18 years completed the questionnaire on 2 occasions as well as the Dermatology Life Quality Index (DLQI). The CECA questionnaire showed good internal consistency (Cronbach's α values of 0.86 and 0.91 in the emotional and sexual activity dimensions) and good testretest reliability (intraclass correlation coefficient 0.76 emotional dimension, 0.82 sexual activity dimension). Patients with de novo lesions and those with more extensive lesions and larger number of warts showed poorer health-related quality of life. CECA and DLQI scores correlated moderately. Patients whose lesions cleared at follow-up or with a reduction of ≥ 50% showed a better improvement of health-related quality of life. The CECA questionnaire is a valid, reliable and sensitive tool for the assessment of health-related quality of life in patients with anogenital warts.

show abstract

Combination of qualitative and quantitative methods for developing a new Health Related Quality of Life measure for patients with anogenital warts

Abstract: Background: Anogenital warts are the most easily recognized sign of genital Human Papilloma Virus infection. The objective was to develop a short, valid and reliable questionnaire to measure Health Related Quality of Life (HRQL) in patients with anogenital warts.

Cited by 35 publications

References 16 publications

HPV and Genital Warts among Peruvian Men Who Have Sex with Men and Transgender People: Knowledge, Attitudes and Treatment Experiences

HPV and Genital Warts among Peruvian Men Who Have Sex with Men and Transgender People: Knowledge, Attitudes and Treatment Experiences

The quality of life of patients with genital warts: a qualitative study

Validation and Clinical Use of the CECA, a Disease-specific Quality of Life Questionnaire for Patients with Anogenital Condylomata Acuminata

Contact Info

Product

Resources

About