Combination of fabric phase sorptive extraction with UHPLC-ESI-MS/MS for the determination of adamantine analogues in human urine

Sidiropoulou, Georgia; Kabir, Abuzar; Furton, Kenneth G.; Kika, Fotini S.; Fytianos, K.; Tzanavaras, Paraskevas D.; Zacharis, Constantinos K.

doi:10.1016/j.microc.2022.107250

Cited by 13 publications

(4 citation statements)

References 41 publications

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“…The SPE-UHPLC-MS/MS method was validated using simulated drinking water samples in terms of linearity, accuracy and precision, limit of detection (LOD) and quantitation (LOQ) (Sidiropoulou et al 2022 ). The correlation coefficients of calibration curves were higher than 0.99 in all cases indicating acceptable linearity in the studied concentration range of LOQ – 80 ng mL − 1 .…”

Section: Resultsmentioning

confidence: 99%

Chemometric Optimization of SPE for the Determination of Multiclass Pesticides in Portable Water Samples by UHPLC-MS/MS

Drimaropoulou,

Christophoridis,

Zacharis

et al. 2024

Bull Environ Contam Toxicol

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This study aimed on the development of a SPE-UHPLC-MS/MS method for the simultaneous determination of pesticide residues in drinking water samples. A chemometric approach was applied to optimize the efficiency of the SPE pretreatment procedure. This study involved (i) the application of a Full Factorial Design for the screening of the significant factors, (ii) the application of a Central Composite Design for the determination of the optimal conditions and (iii) the evaluation and validation of the significance of the statistically proposed models. Oasis HLB cartridges were used for the extraction. The optimum sample volume was 300 mL and the elution solvent 3 mL of the mixture of methanol:ethylacetate 70:30 v/v. The method was validated according to the international guidelines. Recoveries were ranged from 63 to 116% and the detection limits were between 0.1 and 1.5 pg mL− 1. The validated method could be used in routine analysis for pesticides screening.

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Section: Resultsmentioning

confidence: 99%

Chemometric Optimization of SPE for the Determination of Multiclass Pesticides in Portable Water Samples by UHPLC-MS/MS

Drimaropoulou,

Christophoridis,

Zacharis

et al. 2024

Bull Environ Contam Toxicol

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“…The amazing benefits of FPSE as a new-generation sample preparation technique were further manifested in a study presented by G. Sidiropoulou et al [65], where FPSE was combined with UPLC-ESI-MS/MS to monitor the presence of residual antiviral drugs, including amantadine, memantine, and rimantadine in human urine. Sol-gel poly(propylene glycol)-poly(ethylene glycol)-poly(propylene glycol)-coated FPSE membranes reached extraction equilibrium in just 20 min, thanks to the rapid mass transfer of the target analytes from the bulk of the sample to the FPSE membrane due to the engineered affinity of the sol-gel sorbent towards the target analytes via different intermolecular interactions and the sponge-like porous structure of the sol-gel sorbent.…”

Section: Fabric Phase Sorptive Extraction (Fpse)mentioning

confidence: 99%

New Challenges in (Bio)Analytical Sample Treatment Procedures for Clinical Applications

et al. 2023

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The primary cause of poor and ambiguous results obtained from the bioanalytical process is the sample pre-treatment, especially in clinical analysis because it involves dealing with complex sample matrices, such as whole blood, urine, saliva, serum, and plasma. So, the aim of this review is to focus attention on the classical and new techniques of pre-treatment for biological samples used in the bioanalytical process. We discussed the methods generally used for these types of complex samples. Undoubtedly, it is a daunting task to deal with biological samples because the analyst may encounter a substantial loss of the analytes of interest, or the overall analysis may be too time-consuming. Nowadays, we are inclined to use green solvents for the environment, but without sacrificing analytical performance and selectivity. All the characteristics mentioned above should be added to the difficulty of the withdrawal of samples like blood because it can be an invasive practice. For these reasons, now we can also find in the literature the use of saliva as alternative biological samples and new techniques that do not require substantial sample pre-treatment, such as fabric phase sorptive extraction (FPSE). The text has been divided into the following two distinct parts: firstly, we described clinical applications under different subsections, such as anticancer drugs, antibiotics, vitamins, antivirals, non-steroidal anti-inflammatory drugs, statin, imidazoles, and triazoles. The second part is dedicated to sample preparation techniques for diagnostic purposes and is divided into the following different sample preparation techniques: solid-phase microextraction (SPME), microextraction by packed sorbent (MEPS), dispersive liquid–liquid microextraction (DDLME), and fabric phase sorptive extraction (FPSE).

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“…The FPSE membrane has a high absorbent capacity, which allows for rapid extraction kinetics and pH resistance ranging from 1 to 12 without affecting extraction yield. Additionally, FPSE has the potential to tune the polarity or selectivity of FPSE membrane by selecting the appropriate substrate either hydrophobic or hydrophilic [22] , [23] . In FPSE, the sorbent is covalently bonded to the substrate surface, which is typically a fabric substrate that provides great chemical, solvent, and thermal stability.…”

Section: Introductionmentioning

confidence: 99%

Fabric phase sorptive extraction-gas chromatography-mass spectrometry for the determination of favipiravir in biological and forensic samples

Jain

Kabir

et al. 2023

Advances in Sample Preparation

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Combination of fabric phase sorptive extraction with UHPLC-ESI-MS/MS for the determination of adamantine analogues in human urine

Cited by 13 publications

References 41 publications

Chemometric Optimization of SPE for the Determination of Multiclass Pesticides in Portable Water Samples by UHPLC-MS/MS

Chemometric Optimization of SPE for the Determination of Multiclass Pesticides in Portable Water Samples by UHPLC-MS/MS

New Challenges in (Bio)Analytical Sample Treatment Procedures for Clinical Applications

Fabric phase sorptive extraction-gas chromatography-mass spectrometry for the determination of favipiravir in biological and forensic samples

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