Combination of Common Problem in a Rare Disease: Right Iliac Fossa Pain in a Chronic Myeloid Leukemia Patient

Ramzee, Ahmed Faidh; Sameer, Mohammad; Khan, Mohammad Burhan; Ali, Syed Muhammad; Zarour, Ahmad

doi:10.7759/cureus.11523

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…This symptomatology is consistent with findings in other studies, highlighting the commonality of these symptoms in conditions presenting with right iliac fossa pain. 12,13 The overlap of symptoms with various conditions, as discussed in Rajendran's 2015 study, underscores the diagnostic challenges and potential for misdiagnosis in such cases. 13,14 The laparotomy findings in our study, where acute suppurative appendicitis was diagnosed in 68% of cases, reflect the prevalence of appendicitis as a common cause of right iliac fossa pain.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic dilemma of right iliac fossa pain in females: a prospective study of 100 cases

Sayem,

Akter,

Karim

et al. 2024

Int Surg J

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Background: Right iliac fossa (RIF) pain in females presents a significant diagnostic challenge due to the wide range of potential underlying causes. This study aims to elucidate the complexities and diagnostic dilemmas associated with RIF pain in females, focusing on the prevalence of various conditions, the utility of laboratory markers, and the outcomes of surgical interventions. Methods: This prospective study was conducted at Shaheed Tajuddin Ahmed Medical College Hospital, Gazipur, Bangladesh and involved 100 female patients provisionally diagnosed with acute appendicitis. The study included females aged 12 years and above, presenting with symptoms suggestive of acute appendicitis and who were operable. Patients underwent clinical evaluations, laboratory testing, and, where indicated, surgical intervention, including appendectomy. Data were analyzed using SPSSV.19, with findings presented in table format. Results: The most common presenting symptoms were central abdominal pain shifting to RIF, nausea, vomiting, and pyrexia (45%). Laparotomy findings indicated acute suppurative appendicitis in 68% of cases. Appendicectomy results showed a 61% positive diagnosis rate for appendicitis, with 23% negative appendicitis findings. Laboratory results revealed leukocytosis (>11000/mm3) in 66% and a neutrophil count of ≥70% in 71% of the cases. Histopathological analysis post-appendectomy revealed 57.14% acute appendicitis, 15.48% gangrenous appendicitis, and 27.38% normal vermiform appendix. Conclusions: The study highlights the diagnostic challenges in females presenting with RIF pain, with a significant rate of negative appendicitis diagnoses post-appendectomy. The findings underscore the need for a comprehensive diagnostic approach and suggest the potential utility of laboratory markers in supporting diagnoses. The study advocates for improved diagnostic criteria and methods to enhance accuracy and patient outcomes.

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Section: Discussionmentioning

confidence: 99%

Diagnostic dilemma of right iliac fossa pain in females: a prospective study of 100 cases

Sayem,

Akter,

Karim

et al. 2024

Int Surg J

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“…If patients with leukemia continue to pay attention to their advanced pain, they will virtually feel more intense pain, so patients with advanced leukemia are advised not to concentrate their attention and vision on pain, but can rely on certain measures to transfer their vision to reduce the pain aggravation caused by excessive attention to pain. Nursing staff can chat with patients on some topics of interest, and transfer their attention through heart-to-heart talk, reading books, watching movies and TV plays, and meditation training [14] . During the period of attention diversion for patients with advanced stage pain of leukemia, their interests, hobbies, and personality traits should be known so as to make them feel better, and recommend favorite TV plays, books, newspapers and magazines for patients, so as to better motivate patients to concentrate and play a role in relieving pain.…”

Section: Divert Attention Methodsmentioning

confidence: 99%

A Brief Review of the Progress of Research on Late Pain Care in Patients with Leukemia

2022

FMSR

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Leukemia is a general term for malignant diseases of the blood system. It is a group of primary malignant tumors of the blood system. Most of the diseases begin in the bone marrow, resulting in the release of a large number of abnormal blood cells into the peripheral blood, resulting in a series of clinical symptoms and signs. At present, the exact cause of leukemia is not clear, most of the genetic factors and environmental (non-genetic) factors combined effect of the result. There are four main types of leukemia: acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphoblastic leukemia (CLL), and chronic myeloid leukemia (CML). The development of the above-mentioned malignant hematologic diseases to the end stage often causes multiple organ dysfunction and pain. Late pain causes severe body drain and affects the patient's quality of life. In addition to conventional tumor analgesia, pain nursing is also very important in pain management of patients with advanced hematopathy. This paper reviews the literature of late pain nursing for patients with leukemia in recent years, and makes a review in order to provide some reference for the clinical late pain nursing for patients with leukemia.

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“…Intestinal edema ensues with the subsequent dissolution of the mucosal integrity allowing for bacterial invasion [ 1 ]. Specific criteria have helped providers diagnose typhlitis as other abdominal conditions are not easily differentiated, which can cause a delay in treatment resulting in further complications [ 2 ]. Early diagnosis is critical as literature reports mortality rates as high as 50% [ 3 - 4 ].…”

Section: Introductionmentioning

confidence: 99%

Neutropenic Enterocolitis in a Patient With Acute Myeloid Leukemia

Becker¹,

Tafader²,

Bath³

2022

Cureus

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Neutropenic enterocolitis (NE) is a medical emergency that occurs in neutropenic patients characterized by diffuse circumferential mural thickening predominantly involving the cecum. It is not easily differentiated from various other abdominal conditions (i.e., appendicitis, intussusception, ischemic colitis, small bowel obstruction, pseudomembranous colitis, and viral gastroenteritis), but clinicians should be aware of the diagnostic criteria in order to assist with prompt diagnosis. Although standard treatment has yet to be established, it is necessary to initiate early supportive care to reduce mortality risk. Here we present a case of NE with small bowel obstruction in a patient with acute myeloid leukemia (AML). Clinical findings and CT abdomen/pelvis were consistent with NE. Unfortunately, the patient succumbed to the illness.

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Combination of Common Problem in a Rare Disease: Right Iliac Fossa Pain in a Chronic Myeloid Leukemia Patient

Cited by 3 publications

References 14 publications

Diagnostic dilemma of right iliac fossa pain in females: a prospective study of 100 cases

Diagnostic dilemma of right iliac fossa pain in females: a prospective study of 100 cases

A Brief Review of the Progress of Research on Late Pain Care in Patients with Leukemia

Neutropenic Enterocolitis in a Patient With Acute Myeloid Leukemia

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