Combination Herbal Expectorants in Pediatric Practice

Мельникова, И. М.; Мизерницкий, Ю. Л.

doi:10.21518/2079-701x-2018-2-93-97

Cited by 11 publications

(4 citation statements)

References 7 publications

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“…РОССИЙСКИЙ ВЕСТНИК ПЕРИНАТОЛОГИИ И ПЕДИАТРИИ, 2019; 64: (6) ROSSIYSKIY VESTNIK PERINATOLOGII I PEDIATRII, 2019; 64: (6) активных веществ (энкефалинов, эндорфинов, пептидов, кининов), участвующих в регуляции болевых ощущений, проницаемости сосудов и других процессов, что обеспечивает обезболивающее и отвлекающее действие препарата при воспалительных процессах в глотке при ОРВИ [13].…”

Section: After Taking the Drug Ascoril Examiner Relief Of Obstructiounclassified

“…РОССИЙСКИЙ ВЕСТНИК ПЕРИНАТОЛОГИИ И ПЕДИАТРИИ, 2019; 64: (6) ROSSIYSKIY VESTNIK PERINATOLOGII I PEDIATRII, 2019; 64: (6) жижающего мокроту, и одновременно препарата, подавляющего кашель, может вызвать не только эффект «заболачивания легких», но и привести к асфиксии, особенно у ребенка 1-2-го года жизни с последствиями перинатального повреждения нервной системы [9,10].…”

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“…РОССИЙСКИЙ ВЕСТНИК ПЕРИНАТОЛОГИИ И ПЕДИАТРИИ, 2019; 64: (6) ROSSIYSKIY VESTNIK PERINATOLOGII I PEDIATRII, 2019; 64: (6) В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ характер; он эффективно купирует бронхоспазм, снижает сопротивление в дыхательных путях, увеличивая объем форсированного выдоха за 1-ю секунду (ОФВ 1 ) и жизненную емкость легких (ЖЕЛ). Кроме того, препарат стимулирует митотическую активность и восстановление реснитчатого эпителия дыхательных путей, активирует продукцию сурфактанта [12].…”

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Advantages and disadvantages of combined mucolytic therapy in children

Мизерницкий

Shakhnazarova

2020

Ross. vestn. perinatol. pediatr.

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The article discusses in detail advantages and disadvantages of combined mucolytic therapy in children, the requirements for the composition and purpose of such drugs. Such drug as Ascoril expectorant is considered to be a successful combination, pathogenetic mechanisms of the synergistic action of its components. The clinical experience of Ascoril expectorant application demonstrated its high clinical efficacy and safety, which makes it the first choice for bronchitis, mild bronchial obstruction in outpatient pediatric practice

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Advantages and disadvantages of combined mucolytic therapy in children

Мизерницкий

Shakhnazarova

2020

Ross. vestn. perinatol. pediatr.

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“…Преимущество фитопрепаратов заключается в том, что биологически активные вещества растений органичнее включаются в обменные процессы организма человека, чем синтетические препараты. Следствием этого является лучшая переносимость, меньшая частота побочных эффектов и осложнений [11][12][13][14][15]. Это обусловлено их природным происхождением и оправдывает возможность сочетания их с синтетическими мукоактивными препаратами для повышения эффективности отхаркивающей терапии и ускорения очищения бронхиального дерева.…”

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Modern combined plant remedies in pulmonologist’s practice

Мизерницкий¹,

Сулайманов²

2019

Med. sov.

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The article deals with topical issues of secretolytic therapy for coughing in adults and children. Special attention is paid to modern herbal expectorants produced at high-tech pharmaceutical production, which has a certificate of GMP (Good Manufacturing Practice). Today these are well studied products containing extracts of thyme, primrose and ivy, the mechanisms of action of which are well studied in vivo and in vitro studies. Among these herbal medicines, one of the well studied is Bronchipret®. Its high clinical efficacy and good tolerability of treatment for adults and children is shown in large multicenter studies, including those performed according to the «gold standard» of evidence-based medicine, randomized, double-blind, placebo-controlled.

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Individually orientated choice of mucolytic drug for coughing in a child with acute respiratory viral infections

Мельникова

Мизерницкий²

2019

Med. sov.

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Coughing in acute respiratory infections, regardless of the level of infection: upper or lower respiratory tract is a frequent clinical symptom in childhood. The analysis of the modern literature and the data of the authors’ own researches testify to the fact that the prescription of mucoactive therapy in a complex of therapeutic measures (etiotropic, basic therapy, bronchopulmonary drainage, etc.).) should be differentiated and determined not only by the nature and severity of coughs, separated sputum, but also by individual characteristics of the patient, the severity and course of bronchopulmonary pathology, the age of the child, the presence of adverse environmental factors (in particular, passive smoking), the level of compliance with the patient. The use of combined medications simultaneously influencing various pathogenetic mechanisms of inflammation and coughing becomes a promising direction of mucoactive therapy. One of them is Eucabal® syrup containing liquid extracts of thyme and plantain. Due to the synergy of its components, Eucabal® syrup has an expectorant and anti-inflammatory effect, which is important in the initial period of acute respiratory viral infections (tracheitis, bronchitis tracheobronchitis), especially in dry, painful cough with hard-to-remove sputum. In case of acute respiratory viral infections accompanied by a wet cough with a viscous, difficult to separate sputum, mucolytic agents are shown first of all. One of the modern widely used drugs of this group is acetylcysteine (ESPA-NAC®) in a convenient dosage form.

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Combination Herbal Expectorants in Pediatric Practice

Cited by 11 publications

References 7 publications

Advantages and disadvantages of combined mucolytic therapy in children

Advantages and disadvantages of combined mucolytic therapy in children

Modern combined plant remedies in pulmonologist’s practice

Individually orientated choice of mucolytic drug for coughing in a child with acute respiratory viral infections

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