Combating medical device fouling

Harding, Jacqueline L.; Reynolds, Melissa M.

doi:10.1016/j.tibtech.2013.12.004

Cited by 217 publications

(177 citation statements)

References 71 publications

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“…[87][88][89] Such antimicrobial surfaces have great potentials for combating infections in the areas such as medical devices, clinical treatments and so forth. [90][91][92] For successful fabrication of antimicrobial surfaces, there are two convenient methods for introducing antimicrobial cationic polymers: one is the covalent modification and the other is the noncovalent self-assembly. In recent years, lots of research works have employed reversible chemistry into the surfaces in molecular level or modified their mesoscopic structures for improving their antimicrobial performances.…”

Section: Antimicrobial Surfacesmentioning

confidence: 99%

Antimicrobial cationic polymers: from structural design to functional control

Yang

Cai

Huang

et al. 2017

Polym J

197

174

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Antimicrobial cationic polymers mainly contain two functional components: the cationic groups and the hydrophobic groups. The antimicrobial activity is influenced by the type, amount, location and distribution of these two components. This review summarizes the designs and syntheses of antimicrobial cationic polymers by controlling the above two factors. It involves the structural designs from primary to secondary structures, from covalent to noncovalent syntheses and from bulk to surface. Furthermore, it will discuss how to advance structural designs toward functional controls for optimizing the antimicrobial performances and biocompatibility of antimicrobial cationic polymers. It is anticipated that this review will provide some guidelines for developing molecular engineering of antimicrobial cationic polymers with tailor-made structures and functions.

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Section: Antimicrobial Surfacesmentioning

confidence: 99%

Antimicrobial cationic polymers: from structural design to functional control

Yang

Cai

Huang

et al. 2017

Polym J

197

174

View full text Add to dashboard Cite

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“…This phenomenon causes serious technological and economic problems in various fields or processes such as naval transportation, aquaculture, petroleum industries, medical devices, bioreactors or water distribution networks, and wastewater plants (Fitridge et al 2012;Harding and Reynolds 2014). Marine organisms constitute a good source of antifouling molecules.…”

Section: Qsi As Anti-biofouling Agentsmentioning

confidence: 99%

Bioactive Natural Products: An Overview, with Particular Emphasis on Those Possessing Potential to Inhibit Microbial Quorum Sensing

Kothari

Patel

Joshi

2017

Microbial Applications Vol.2

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Bioactive natural products have formed the core of most ancient systems of healthcare and medicine. Crude natural preparations have been used for relief in a variety of infections and disease conditions. This review starts with a general description of the bioactive natural products, followed by the information on natural products being used for dealing with infectious microorganisms. In the latter section, much emphasis has been on the natural products capable of disrupting microbial communication, i.e., quorum sensing. Quorum sensing inhibitors are being expected to emerge as an important class of novel therapeutic agents in the future. Few other issues, important while performing lab experiments with natural products, are also touched upon.

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“…[1][2][3] It has been reported that PEGylation improves the quality of various kinds of materials used for biomedical application in such way of increasing protein/peptide stability, promoting efficient drug delivery, and increasing biocompatibility toward nonfouling medical devices. [4][5][6][7] Versatile functional groups at the terminal sites of PEG polymers enable the attachment of various biomolecules such as proteins, nucleic acids, and carbohydrates. [8][9][10][11] Of the numerous functional PEG polymers, heterobifunctional PEG derivatives are often used as cross-linkers or spacers between two biomolecules.…”

Section: Introductionmentioning

confidence: 99%

Efficient Synthesis and Characterization of Monoprotected Symmetrical Poly(Ethylene Glycol) Diamine

Jeong

Youn

Nam

et al. 2017

Bulletin Korean Chem Soc

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Solid-phase synthesis of monoprotected poly(ethylene glycol) (PEG) diamine is demonstrated. 2-Chlorotrityl chloride (2-CTC) resin was used as a solid support for inducing monofunctionalization using excess PEG diamine. Fmoc-monoprotected PEG was prepared from 2-CTC resin and fully characterized by high-performance liquid chromatography and electrospray ionization mass spectrometry. We envision that this strategy will provide an efficient method of preparing various kinds of heterobifunctional PEG molecules without a need for further purification steps.

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Combating medical device fouling

Cited by 217 publications

References 71 publications

Antimicrobial cationic polymers: from structural design to functional control

Antimicrobial cationic polymers: from structural design to functional control

Bioactive Natural Products: An Overview, with Particular Emphasis on Those Possessing Potential to Inhibit Microbial Quorum Sensing

Efficient Synthesis and Characterization of Monoprotected Symmetrical Poly(Ethylene Glycol) Diamine

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