Combating Infectious Diseases with Computational Immunology

Husáková, Martina

doi:10.1007/978-3-319-24306-1_39

Cited by 4 publications

(3 citation statements)

References 36 publications

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“…There is increasing evidence that immune behavior in health and diseases is affected by socioeconomic status (SES), genetic, epigenetic, molecular, cellular, and environmental modulatory factors (21). A better understanding of these multifactorial linkages will be almost impossible without exploiting all aspects of immunology; clinical, experimental, and computational immunology strategies (22). The need to develop novel animal models that mimic complex diseases is critical for creating new mathematical and computational models to predict immune responses (22,23).…”

Section: Toward a Holistic Immunology Educationmentioning

confidence: 99%

“…A better understanding of these multifactorial linkages will be almost impossible without exploiting all aspects of immunology; clinical, experimental, and computational immunology strategies ( 22 ). The need to develop novel animal models that mimic complex diseases is critical for creating new mathematical and computational models to predict immune responses ( 22 , 23 ). This alone may not answer the challenges in immunology research but will have to go along with the development and availability of technological innovations with minimal sample preparation steps, shorter runtimes, and high-quality results (higher sensitivity, specificity, and accuracy).…”

Section: Toward a Holistic Immunology Educationmentioning

confidence: 99%

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Prospects of Immunology Education and Research in Developing Countries

Kwarteng

Sylverken

Antwi‐Berko

et al. 2021

Front. Public Health

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The burden of infectious disease in developing countries is substantially higher than in developed nations. Reasons include poor health care infrastructure and deficiencies in public understanding of infectious disease mechanisms and disease prevention. While immunology education and research have an enviable role in understanding host-pathogen interactions, training programs in immunology remain fully integrated into the curricula of higher institutions, and by extension, to high schools of developing nations. Therefore, we discussed the need to make major investments in immunology research and research training into all natural sciences teaching curricula, particularly in developing countries.

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Section: Toward a Holistic Immunology Educationmentioning

confidence: 99%

Section: Toward a Holistic Immunology Educationmentioning

confidence: 99%

Prospects of Immunology Education and Research in Developing Countries

Kwarteng

Sylverken

Antwi‐Berko

et al. 2021

Front. Public Health

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“…Alzheimer's disease has been predominantly studied from the perspective of chemistry and medicine [25][26][27][28][29][30]. Since so much is unknown about AD, some articles seek to predict these unknowns [3][4][5]31,32], while others use artificial intelligence or advanced decision-making methods to address related issues [33][34][35]. Research on AD is also very closely associated with the financial costs of treatment, so there are many publications in this area as well [36][37][38][39][40][41][42].…”

Section: Related Workmentioning

confidence: 99%

The Business Process Model and Notation Used for the Representation of Alzheimer’s Disease Patients Care Process

Kopecký

Tomášková

2020

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Currently, the number of patients with neurological diseases is increasing, especially those older than 65 suffering from Alzheimer’s disease. This development increases the emphasis on understanding and mapping treatment and care processes, not only for the elderly. Service providers (of both treatment and care) are under general pressure to decrease charges and maintain or improve existing levels of care. This situation is significantly influenced by a comprehensive knowledge of the whole process and its values. This publication therefore aims to describe the fundamental procedural aspects of caring for patients with Alzheimer’s disease, using Business Process Model and Notation (BPMN). It also aims to show the possibilities of using BPMN in the description of treatment and care. Modeling of the business process is more frequently being applied not only by businesses but also by scientists involved in process models. It is used to model medical topics, with approximately 10% of its publications only, and most of these publications deal only with clinical pathways, not with overall treatment and care processes. However, the BPMN model allows the whole process of medical and nonmedical care for patients with Alzheimer’s disease to be described, including the decomposition of partial activities into individual threads and sub-processes or atomic tasks. This paper presents the BPMN modeling and mapping of the specific care path for neurodegenerative patients. The text provides a new perspective on the BPMN modeling of Alzheimer’s disease. The presented model offers the option of expanding treatment cost calculation to simulate the process using graphical tools and languages. The overall view of this system creates a much more complex concept of the system and its surroundings.

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