Colposcopic evaluation of cervix with persistent inflammatory Pap smear: A prospective analytical study

Dasari, Papa; Rajathi, S.; Kumar, Surendra V

doi:10.4103/1742-6413.67112

Cited by 22 publications

(30 citation statements)

References 6 publications

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“…The incidence of CIN and invasive carcinoma in women with persistent inflammatory pap smears over just 2 weeks was found to be 20.6% and 0.7%, respectively, in a study by Dasari et al [16] Hence, by waiting for a longer period of time before repeating the pap smear may lead to a delay in diagnosis of CIN in a high percentage of cases.…”

Section: Discussionmentioning

confidence: 95%

Persistent inflammation on Pap smear: Does it warrant evaluation?

et al. 2011

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Section: Discussionmentioning

confidence: 95%

Persistent inflammation on Pap smear: Does it warrant evaluation?

et al. 2011

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“…We included repeated cervicitis as a colposcopy indication because in a recent study, a 16.67% incidence of CIN in women with persistent inflammatory pap smear was reported (Bhutia et al, 2011). The incidences of CIN and invasive carcinoma in women with persistent inflammatory pap smears over just 2 weeks were found to be 20.6% and 0.7%, respectively, in another study (Dasari et al, 2010). One must not see a report of inflammation on pap smear in isolation and ignore it as being insignificant.…”

Section: Reliability Of Colposcopy In Turkey: Correlation With Pap Smmentioning

confidence: 99%

Reliability of Colposcopy in Turkey: Correlation with Pap Smear and 1-year Follow Up

Mesci-Haftaci

Ankaralı²,

Çağlar³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: A cytologic reading of a Papanicolaou (pap) smear followed, if the result is positive, by a colposcopic search for abnormal cells is the most common screening method for cervical cancer used worldwide. We aimed to present the correlation of smear and colposcopic findings with 6-to 12-month follow-up results and related factors in women who underwent colposcopy in Turkey. Materials and Methods: The study population consisted of women who attended the gynecology department and were referred for colposcopic evaluation in 2011-2012. A total of 232 women between ages 17 and 68 years were included. Colposcopy indications were ASCUS and higher lesions at cervical smear, macroscopic suspicious lesions, post-coital bleeding history with suspicious smear, and repeated cervical inflammation. All patients were recalled for 6-to 12-month follow-ups. Results: The most common colposcopy indication was ASCUS, and the most common biopsy result was inflammation. Nearly half of the patients returned for the control 6-month follow-up, and almost 20% of patients for a 1-year follow up. Conclusions: Colposcopic biopsy is an effective method in indicated patients but is not sufficient in itself if awareness of the subject is not raised in the population. One of the most important aims of cancer screening programs should be enabling patients in developing countries to take responsibility. Patients must be encouraged to apply to the hospital for better disease control.

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“…Patients already diagnosed as cases of cervical cancer or treated for it were excluded from the study. The sample size was calculated using power analysis and sample size software based on different techniques as described in studies, the sample size was calculated to be n=145 10,11,12,13,14,15 Findings were noted on a proforma (colposcopy findings, cytology and histopathology reports). Abnormal cytology included ASCUS, LSILS, HSILS and invasive carcinoma.…”

Section: Methodsmentioning

confidence: 99%

“…23 A prospective study of India of 2008 shows that there is a lack of agreement between cytology and histopathology and it concludes that in patients who have persistent inflammatory pap smear can have cervical intraepithelial neoplasia 11 , according to a study there was agreement between pap smear and cervical biopsy ( k=0.5 ) 12 and another study concluded that a high agreement between cytology and histopathology exists of 82%…”

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confidence: 99%

Cervical Diseases; To Compare the Efficacies of Pap Smear Cytology, Colposcopy and Histopathology, in Gynaecological Diagnosis

Lakhwani

Yasir

Amjad

et al. 2016

TPMJ

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ABSTRACT… Objectives:The aim of our study is to compare the efficacies of Pap smear cytology, colposcopy and histopathology, in diagnosis of cervical diseases. Study Design: Cross sectional cohort study. Period: One year from June 2013 to June 2014. Setting: Tertiary care hospital in Karachi, Pakistan. Method: The patient population n=145 consisted of women ranging from age 18 to 80 years old, who had come to the outpatient clinics for a variety of symptoms. Pap smear, colposcopy and histopathology was done for women who had symptoms like recurrent vaginal discharge, postcoital bleeding and other diseases of the cervix. Findings were noted on a proforma and all the patients signed a duly informed consent. Data was analyzed using SPSS version 23. Results: The mean age was 45 +/-9 years (between 24 -75 years), the parity was 5 +/-4, normal colposcopy findings were found in n= 66 women, while abnormal findings were found in n=79 women. In the abnormal colposcopic finding group n=63 had abnormal histopathology (p<0.001) abnormal histopathology was found in n=11 women who had normal colposcopic findings (16.67% false negative), the calculated sensitivity and specificity of colposcopy was determined to be 86% and 79%. For pap smear abnormality was found in n= 49 patients, out of which n=29 had abnormal findings on histopathology as well. And for colposcopy and pap smear out of n= 78 patients who had abnormal colposcopic findings, abnormal pap smear was found in only n= 28 patients. And out of those who had normal colposcopy n= 67, n= 21 had abnormal pap smear (False positivity of 31.34%) similarly out of those who had normal pap smear n= 96, n= 44 had abnormal histopathology (false negativity of 45.83%). The calculated sensitivity and specificity of pap smear was 38.8% and 71.8% respectively. Conclusion: We have concluded that there is a strong correlation between findings of colposcopy and histopathological diagnosis, but when it comes to the diagnosis made by pap smear and colposcopy and pap smear and histopathology the correlation is weak and not consistent. Key words:Pap smear, colposcopy, histopathology, cervix, correlation, cancer. Article Citation: Lakhwani MB, Yasir R, Amjad A, Ali Z. Cervical diseases; to compare the efficacies of pap smear cytology, colposcopy and histopathology, in gynaecological diagnosis.

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Colposcopic evaluation of cervix with persistent inflammatory Pap smear: A prospective analytical study

Cited by 22 publications

References 6 publications

Persistent inflammation on Pap smear: Does it warrant evaluation?

Persistent inflammation on Pap smear: Does it warrant evaluation?

Reliability of Colposcopy in Turkey: Correlation with Pap Smear and 1-year Follow Up

Cervical Diseases; To Compare the Efficacies of Pap Smear Cytology, Colposcopy and Histopathology, in Gynaecological Diagnosis

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