Colour Doppler imaging and polycystic ovary syndrome

Battaglia, Cesare; Volpe, Annibale

doi:10.1093/oxfordjournals.humrep.a019282

“…We agree with Pan et al (18) in that quantification of Doppler signals within the entire ovary by 3-D CPA histogram analysis appears to be superior to the conventional 2-D Doppler method, although early Doppler ultrasound studies (33,34) could also demonstrate the increased stromal vascularity in PCOs. Blood flow (FI) and vascularization (VI), as well as both parameters together (VFI), can be studied only with 3-D CPA.…”

Section: Figuresupporting

confidence: 91%

Assessment of three-dimensional sonographic features of polycystic ovaries after laparoscopic ovarian electrocautery

Vizer

¹

,

Kiesel

²

,

Szabó

³

et al. 2007

Fertility and Sterility

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“…Surprisingly, however, in the only follow-up study of mortality in PCOS women, the standardized mortality ratio for stroke was reduced [4]. There are haemodynamic changes in these women : Battaglia et al [5] reported decreased ovarian artery resistance and increased uterine artery resistance. Insulin resistance is a central feature in women with PCOS and in women with asymptomatic polycystic ovaries (PCO), and it is therefore of interest that haemodynamic changes have been demonstrated in the cerebral circulation in diabetic subjects [6] and pancreatectomized dogs [7].…”

Section: Introductionmentioning

confidence: 96%

Internal carotid artery haemodynamics in women with polycystic ovaries

Lakhani

¹

,

Constantinovici

²

,

Purcell

³

et al. 2000

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Although polycystic ovarian syndrome (PCOS) is associated with risk factors for cerebrovascular disease, the available evidence does not demonstrate increased stroke mortality, and it has been suggested that some protective mechanisms must be operating in these women. Haemodynamic changes have been demonstrated in the pelvic vessels and aorta in this syndrome, but there have been no studies of the cerebral circulation. Since insulin resistance is a central feature of PCOS, it is of interest that cerebral blood flow may be altered in diabetic subjects. The present study was designed to assess internal carotid artery haemodynamics in women with PCOS, asymptomatic women with polycystic ovaries (PCO women) and healthy controls. Mean internal carotid pulsatility index, measured using pulsed Doppler ultrasound under standardized conditions, was significantly lower in 35 PCOS and 15 PCO women than in the 18 controls. This was also shown on multiple regression analyses. Peak systolic velocity did not differ between groups. In view of the difficulty of interpreting pulsatility index in low-impedance vascular beds, the 'back' pressure was calculated and found to be lower in women with polycystic ovaries. This is the first demonstration of lower pulsatility index and back pressure (suggestive of reduced vascular tone) in the cerebral circulation of these women, independent of blood pressure, insulin resistance and other endocrine or metabolic factors. Changes in internal carotid haemodynamics may offset the risk of cerebrovascular disease commonly associated with polycystic ovaries.

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“…The syndrome is also associated with risk factors for stroke, including hypertension, obesity and hypercholesterolaemia. There are haemodynamic changes in these women : Battaglia et al [5] reported decreased ovarian artery resistance and increased uterine artery resistance. There are haemodynamic changes in these women : Battaglia et al [5] reported decreased ovarian artery resistance and increased uterine artery resistance.…”

Section: Introductionmentioning

confidence: 99%

Internal carotid artery haemodynamics in women with polycystic ovaries

Lakhani¹,

Constantinovici²,

Purcell³

et al. 2000

View full text Add to dashboard Cite

Although polycystic ovarian syndrome (PCOS) is associated with risk factors for cerebrovascular disease, the available evidence does not demonstrate increased stroke mortality, and it has been suggested that some protective mechanisms must be operating in these women. Haemodynamic changes have been demonstrated in the pelvic vessels and aorta in this syndrome, but there have been no studies of the cerebral circulation. Since insulin resistance is a central feature of PCOS, it is of interest that cerebral blood flow may be altered in diabetic subjects. The present study was designed to assess internal carotid artery haemodynamics in women with PCOS, asymptomatic women with polycystic ovaries (PCO women) and healthy controls. Mean internal carotid pulsatility index, measured using pulsed Doppler ultrasound under standardized conditions, was significantly lower in 35 PCOS and 15 PCO women than in the 18 controls. This was also shown on multiple regression analyses. Peak systolic velocity did not differ between groups. In view of the difficulty of interpreting pulsatility index in low-impedance vascular beds, the 'back' pressure was calculated and found to be lower in women with polycystic ovaries. This is the first demonstration of lower pulsatility index and back pressure (suggestive of reduced vascular tone) in the cerebral circulation of these women, independent of blood pressure, insulin resistance and other endocrine or metabolic factors. Changes in internal carotid haemodynamics may offset the risk of cerebrovascular disease commonly associated with polycystic ovaries.

show abstract

Colour Doppler imaging and polycystic ovary syndrome

Cited by 4 publications

References 6 publications

Assessment of three-dimensional sonographic features of polycystic ovaries after laparoscopic ovarian electrocautery

Assessment of three-dimensional sonographic features of polycystic ovaries after laparoscopic ovarian electrocautery

Internal carotid artery haemodynamics in women with polycystic ovaries

Internal carotid artery haemodynamics in women with polycystic ovaries

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