Colorimetric estimation of alfuzosin hydrochloride in pharmaceutical preparation based on computational studies

Abstract

Computational and theoretical studies were done electronically and geometrically to find a suitable, selective and sensitive coupling agent applicable for diazocoupling estimation of alfuzosin hydrochloride (ALF).

Spectrophotometric quantitative analysis of remdesivir using acid dye reagent selected by computational calculations

“…The compounds were computationally optimized and the energy in the optimized conformations was calculated. Also, the binding energy of interaction between RV and various acid dyes, ΔE, was calculated using the following equation [11] : …”

“…Computational chemistry offers good approach for accurate predictions before the actual experiments are performed. In general, computational calculations provide complementary data to the experimental data [11] , [12] . With the progress of computational studies, the authors believed to introduce specific computational and theoretical studies for choosing the sensitive acid dye for a more precise color-based spectrophotometric method.…”

Green adherent spectrophotometric determination of molnupiravir based on computational calculations; application to a recently FDA-approved pharmaceutical dosage form

“…Computational chemistry represents an integral approach, in HPLC [4] , [5] , spectrophotometry [6] , [7] and electrochemistry [8] , to the development of greener methods based on theoretical testing of compound interactions and reducing the use of toxic solvents [9] . Many analytical methods have been developed to demonstrate the quality of the drug materials including HPLC [10] , TLC [11] , specroflorimetry [12] , [13] , [14] , [15] , [16] , [17] as well as spectrophotometry [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] . Table 1.…”

An ultra-sensitive electrochemical sensor based on MOF-derived ZnO/Co3O4decorated on graphene for low-level monitoring of the α1-AR antagonist alfuzosin in tablets and human samples

“…By blocking these receptors, AFZ relaxes the smooth muscles and allows urine to flow more freely. 2,3 AFZ is generally well-tolerated, but it can cause side effects such as dizziness, headache, and hypotension. In rare cases, AFZ can also cause more serious side effects, such as orthostatic hypotension, priapism, and hypersensitivity reactions.…”