Colorimetric detection of methionine based on anti-aggregation of gold nanoparticles in the presence of melamine

Huang, Pengcheng; Gao, Nan; Li, Jianfang; Wu, Fang

doi:10.1016/j.snb.2017.09.092

Cited by 52 publications

(26 citation statements)

References 38 publications

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“…Proteins are known to interact with AuNPs through the formation of a protein corona around particle’s surface. [ 48 ] Therefore, a protein precipitation protocol was used to remove as much proteins as possible, as is commonly done in nanoparticle based colorimetric assays [ 49 ], because their presence hinders the capability of formation, growth and aggregation of particles.…”

Section: Resultsmentioning

confidence: 99%

Paper-Based In-Situ Gold Nanoparticle Synthesis for Colorimetric, Non-Enzymatic Glucose Level Determination

et al. 2020

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Due to its properties, paper represents an alternative to perform point-of-care tests for colorimetric determination of glucose levels, providing simple, rapid, and inexpensive means of diagnosis. In this work, we report the development of a novel, rapid, disposable, inexpensive, enzyme-free, and colorimetric paper-based assay for glucose level determination. This sensing strategy is based on the synthesis of gold nanoparticles (AuNPs) by reduction of a gold salt precursor, in which glucose acts simultaneously as reducing and capping agent. This leads to a direct measurement of glucose without any enzymes or depending on the detection of intermediate products as in conventional enzymatic colorimetric methods. Firstly, we modelled the synthesis reaction of AuNPs to determine the optical, morphological, and kinetic properties and their manipulation for glucose sensing, by determining the influence of each of the reaction precursors towards the produced AuNPs, providing a guide for the manipulation of nucleation and growth. The adaptation of this synthesis into the developed paper platform was tested and calibrated using different standard solutions with physiological concentrations of glucose. The response of the colorimetric signals obtained with this paper-based platform showed a linear behavior until 20 mM, required for glycemic control in diabetes, using the Red × Value/Grey feature combination as a calibration metric, to describe the variations in color intensity and hue in the spot test zone. The colorimetric sensor revealed a detection limit of 0.65 mM, depending on calibration metric and sensitivity of 0.013 AU/mM for a linear sensitivity range from 1.25 to 20 mM, with high specificity for the determination of glucose in complex standards with other common reducing interferents and human serum.

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Section: Resultsmentioning

confidence: 99%

Paper-Based In-Situ Gold Nanoparticle Synthesis for Colorimetric, Non-Enzymatic Glucose Level Determination

et al. 2020

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“…This prompted us to check the possibility to detect histamine directly in a complex matrix such as the wine. Amine content detection in wine is usually performed by means of spectroscopic methods and HPLC‐gas chromatography …”

Section: Resultsmentioning

confidence: 99%

Cellulose‐Based Substrate for SERS‐Promoted Histamine Picomolar Detection in Beverages

et al. 2019

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Histamine is a biogenic amine (BA) playing an important physiological role in human body, even though the assumption of high histamine amount from food and beverages can cause health diseases such as, for example, cutaneous allergy, headache and nausea. In fact, histamine can be present in foods and beverages as the result of microbial metabolism induced by temperatures and storage conditions, so histamine levels are commonly used as an indicator of food safety and quality. In the present contribution, the possibility to detect low concentration of histamine by Surface Enhanced Raman Spectroscopy (SERS) by using silver nanoparticles (AgNPs)-cellulose hybrid substrate has been proposed. An easy procedure for the fabrication of the hybrid supports was developed and SERS effect at different AgNPs amounts was tested. The developed systems allowed detecting histamine down to 10-12 M in aqueous solutions. SERS substrates have been tested directly on two different kinds of commercial white wines, the first one stored in tetra pack and the other one in glass bottles without any pre-treatment procedure. Histamine concentrations in the real samples were obtained by recording the corresponding Raman spectra and confirmed by means of conventional HPLC analysis.[a] Dr.

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“…Basically, the absorption spectra of gold nanoparticles are shifted and the colour of the nanoparticles is changed due to change in their size and aggregation state . The aggregation of Au NPs in the presence of metal ions have great importance for the detection of heavy metal ions in aqueous media.…”

Section: Introductionmentioning

confidence: 99%

Nano Gold Hybrid Polyvinyl Alcohol Films for Sensing of Cu²⁺ ions

et al. 2019

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An efficient and eco‐friendly approach is adopted for the synthesis of highly stable L‐alanine assisted nano gold based polyvinyl alcohol nanocomposite hybrid films (Au/PVA).The –COOH groups of L‐alanine and oxygeneous groups of polyvinyl alcohol are utilized for the synthesis of size controlled gold nanoparticles. The as‐synthesized nanocomposites show rapid and selective detection of Cu2+ ion in aqueous medium. With addition Cu2+ ion to as‐synthesized nanocomposites, the SPR peaks of Au NPs (538 nm) decrease with occurrence of a red shift as well as a new peak is observed at higher wavelength which is due to the aggregation of gold nanoparticles in the nanocomposites hybrid films. Scanning electron microscope (SEM) micrograph and energy dispersive spectroscopy (EDS) reveal the aggregation of gold nanoparticles in the nanocomposite hybrid films. The limit of detection and limit of quantification for Cu2+ ion are 40 nM and 133 nM respectively. This technique for detection of Cu2+ ion in waste water samples is inexpensive and eco‐friendly since no any toxic chemicals are used. In the presence of Cu2+ ion, the colour of the hybrid film is changed hence, this method also involves visual detection of Cu2+ ion without use of electrolyte or transducer. Further, many reported methods represent the in situ monitoring of Cu2+ ion, but the present hybrid film can be used for in situ as well as ex situ monitoring of Cu2+ ion.

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Colorimetric detection of methionine based on anti-aggregation of gold nanoparticles in the presence of melamine

Cited by 52 publications

References 38 publications

Paper-Based In-Situ Gold Nanoparticle Synthesis for Colorimetric, Non-Enzymatic Glucose Level Determination

Paper-Based In-Situ Gold Nanoparticle Synthesis for Colorimetric, Non-Enzymatic Glucose Level Determination

Cellulose‐Based Substrate for SERS‐Promoted Histamine Picomolar Detection in Beverages

Nano Gold Hybrid Polyvinyl Alcohol Films for Sensing of Cu²⁺ ions

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Colorimetric detection of methionine based on anti-aggregation of gold nanoparticles in the presence of melamine

Cited by 52 publications

References 38 publications

Paper-Based In-Situ Gold Nanoparticle Synthesis for Colorimetric, Non-Enzymatic Glucose Level Determination

Paper-Based In-Situ Gold Nanoparticle Synthesis for Colorimetric, Non-Enzymatic Glucose Level Determination

Cellulose‐Based Substrate for SERS‐Promoted Histamine Picomolar Detection in Beverages

Nano Gold Hybrid Polyvinyl Alcohol Films for Sensing of Cu2+ ions

Contact Info

Product

Resources

About

Nano Gold Hybrid Polyvinyl Alcohol Films for Sensing of Cu²⁺ ions