Colorimetric and electrochemical detection platforms for tetracycline based on surface molecularly imprinted polyionic liquid on Mn3O4 nanozyme

ACS Appl. Mater. Interfaces

et al. 2023

An optical monitoring device combining a smartphone with a polychromatic ratiometric fluorescence-colorimetric paper sensor was developed to detect Hg2+ and S2– in water and seafood. This monitoring included the detection of food deterioration and was made possible by processing the sensing data with a machine learning algorithm. The polychromatic fluorescence sensor was composed of blue fluorescent carbon quantum dots (CDs) (BU-CDs) and green and red fluorescent CdZnTe quantum dots (QDs) (named GN-QDs and RD-QDs, respectively). The experimental results and density functional theory (DFT) prove that the incorporation of Zn can improve the stability and quantum yield of CdZnTe QDs. According to the dynamic and static quenching mechanisms, GN-QDs and RD-QDs were quenched by Hg2+ and sulfide, respectively, but BU-CDs were not sensitive to them. The system colors change from green to red to blue as the concentration of the two detectors rises, and the limits of detection (LOD) were 0.002 and 1.488 μM, respectively. Meanwhile, the probe was combined with the hydrogel to construct a visual sensing intelligent test strip, which realized the monitoring of food freshness. In addition, a smartphone device assisted by multiple machine learning methods was used to text Hg2+ and sulfide in real samples. It can be concluded that the fabulous stability, sensitivity, and practicality exhibited by this sensing mechanism give it unlimited potential for assessing the contents of toxic and hazardous substances Hg2+ and sulfide.

Section: Principle Of Integratingsupporting

confidence: 75%

“…The existence of a sharp peak at 2000 cm –1 proves the formation of −CCN in BU-CDs. The peaks at 1640 and 1740 cm –1 are CO in the carboxyl group . The weak absorption peak near 1410 cm –1 is attributed to −OH in the carboxyl group, and the absorption peak of 1230 cm –1 belongs to C–O.…”

Section: Resultsmentioning

confidence: 97%

Machine Learning System To Monitor Hg²⁺ and Sulfide Using a Polychromatic Fluorescence-Colorimetric Paper Sensor

Lü

Chen

ACS Appl. Mater. Interfaces

et al. 2023

“…37,38 Manganese oxide nanoparticles have recently been used as nanozymes, gaining popularity due to their ability to mimic enzymes. [39][40][41] Manganese dioxides of various morphologies, such as MnO 2 nanosheets, 37 BSA-templated MnO 2 nanoparticles, 42 MnO 2 nanorods, 43 MnO 2 nanowires, 44 MnO 2 nanoflowers, 45 MnO 2 nanobelts, 46 MnO 2 nanoflakes 47 and MnO 2 microspheres, 48 have been used as nanozymes.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of MnO₂ sub-microspheres with effective oxidase-mimicking nanozymes for the colorimetric assay of ascorbic acid in orange fruits and juice

2023

“…Molecular imprinting technology is an important bionic technology to fabricate molecularly imprinted polymers (MIPs) simulating the recognition phenomenon in biological molecules . After the template molecule on MIP is eluted off, three-dimensional cavities consistent with the shape and size of the template molecule are remained, and the intermolecular forces required to identify the target are retained, acting as a “key and lock” structure for specific recognition. , Therefore, introducing molecular imprinting onto the surface of nanozymes can not only retain the catalytic signal amplification ability but also improve the poor recognition defect of the latter. , Given the attractive feature, recently, a few efforts have been made on exploring molecularly imprinted nanozymes to construct analytical methods, − demonstrating the potential of combing nanozyme catalysis and MIP recognition in realizing the selective and sensitive detection of analytes. Typically, our group imprinted some MIP sites on peroxidase-like Fe 3 O 4 and developed a colorimetric assay for TC determination .…”

Section: Introductionmentioning

confidence: 99%

Alkali-Etched Imprinted Mn-Based Prussian Blue Analogues with Superior Oxidase-Mimetic Activity and Precise Recognition for Tetracycline Colorimetric Sensing

Zhu

ACS Appl. Mater. Interfaces

et al. 2023

As a typical antibiotic pollutant, tetracycline (TC) is producing increasing threats to the ecosystem and human health, and exploring convenient means for monitoring of TC is needed. Here, we proposed alkali-etched imprinted Mn-based Prussian blue analogues featuring superior oxidase-mimetic activity and precise recognition for the colorimetric sensing of TC. Simply etching Mn-based Prussian blue analogues (Mn-PBAs) with NaOH could expose the sites and surfaces to significantly improve their catalytic activity. Density functional theory calculations were employed to screen the molecularly imprinted polymer (MIP) layer for target identification. Consequently, the designed Mn-PBANaOH@MIP possessed the rich channels for substrates to get in touch with the active Mn-PBANaOH core, showing an excellent catalytic capacity to trigger the chromogenic oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) without the use of H2O2. If TC was introduced, it would be recognized selectively by the MIP shell and masked the channels for TMB access, resulting in the obstruction of the chromogenic reaction. According to this mechanism, selective optical detection of TC was achieved, and performance stability, reusability, and reliability as well as practicability were also verified, promising potential for TC monitoring in complex matrices. Our work not only presents an effective way to enhance the enzyme-like activity of Prussian blue analogues but also provides a facile approach for TC sensing. Additionally, the work will inspire the exploration of molecularly imprinted nanozymes for various applications.