Colorectal Cancer Screening by Double Contrast Barium Enema in Thai People

Lohsiriwat, Varut; Prapasrivorakul, Siriluck; Suthikeeree, Wanwarang

doi:10.7314/apjcp.2012.13.4.1273

Cited by 10 publications

(7 citation statements)

References 24 publications

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“…In both the methods, x-rays are used to observe the colon from outside the body (Pickhardt, 2013;Kuipers and Spaander, 2015). The occurrence of colorectal neoplasm was detected using doublecontrast barium enema (DBEM) screening in people of Thailand and reported a diagnostic outcome of 0.4% for CRC and 0.7% for advanced adenoma (Lohsiriwat et al, 2013). Insigmoidoscopy test for checking cancer, polyps, and other abnormalities using a flexible tube having light at the end is inserted into the lower colon and rectum (Guo et al, 2015).…”

Section: Existing Screening Methods For Colorectal Cancermentioning

confidence: 99%

Nanotechnology in Colorectal Cancer for Precision Diagnosis and Therapy

Brar

Ranjan

Palria

et al. 2021

Front. Nanotechnol.

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Colorectal cancer (CRC) is the third most frequently occurring tumor in the human population. CRCs are usually adenocarcinomatous and originate as a polyp on the inner wall of the colon or rectum which may become malignant in the due course of time. Although the therapeutic options of CRC are limited, the early diagnosis of CRC may play an important role in preventive and therapeutic interventions to decrease the mortality rate. The CRC-affected tissues exhibit several molecular markers that may be exploited as the novel strategy to develop newer approaches for the treatment of the disease. Nanotechnology consists of a wide array of innovative and astonishing nanomaterials with both diagnostics and therapeutic potential. Several nanomaterials and nano formulations such as Carbon nanotubes, Dendrimer, Liposomes, Silica Nanoparticles, Gold nanoparticles, Metal-organic frameworks, Core-shell polymeric nano-formulations, Nano-emulsion System, etc can be used to targeted anticancer drug delivery and diagnostic purposes in CRC. The light-sensitive photosensitizer drugs loaded gold and silica nanoparticles can be used to diagnose as well as the killing of CRC cells by the targeted delivery of anticancer drugs to cancer cells. This review is focused on the recent advancement of nanotechnology in the diagnosis and treatment of CRC.

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Section: Existing Screening Methods For Colorectal Cancermentioning

confidence: 99%

Nanotechnology in Colorectal Cancer for Precision Diagnosis and Therapy

Brar

Ranjan

Palria

et al. 2021

Front. Nanotechnol.

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“…In Asian population also the colon cancer is increasing rapidly Iinuma et al, 2008;Lohsiriwat et al, 2012). The numbers in India is shown in Table 2 (survey area was limited to few cities).…”

Section: Global and India Scenario Of Colon Cancersmentioning

confidence: 99%

Feasibility of Computed Tomography Colonography as a Diagnostic Procedure in Colon Cancer Screening in India

Manjunath

Prabhu²,

Siddalingaswamy

2014

Asian Pacific Journal of Cancer Prevention

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“…Enemas are widely used in nursing care (Yang et al, 2011), primarily to cleanse the intestinal tract before abdominal surgery, especially intestinal surgery (Aslan et al, 2013;Ihedioha, Vaughan, Mastermann, Singh, & Chaudhri, 2013). Enemas are also used as pretreatment before the use of advanced technology for making certain complicated diagnoses, such as colorectal cancer or diverticula of the colon (Lohsiriwat, Prapasrivorakul, & Suthikeeree, 2012;Niikura, Nagata, Shimbo, Akiyama, & Uemura, 2013). Enemas are also effective as treatment for conditions such as constipation (Rodriguez, Nurko, & Flores, 2013), intussusception (Chien, Willyerd, Mandeville, Hostetler, & Bulloch, 2013), and colitis (Flourié et al, 2013).…”

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confidence: 99%

Relationship Between the pH of Enema Solutions and Intestinal Damage in Rabbits

Zhang

et al. 2014

Biological Research For Nursing

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Mechanical enemas can lead to intestinal mucosal injuries and bowel barrier damage, presenting as electrolyte disturbances and functional intestinal disorders. Most researchers believe that the mechanism of injury is related to osmolality, volume and temperature of the solution, infusion pressure, and the composition of the enema tube. We hypothesized that the pH of the enema solution may also contribute to intestinal damage. We administered enema solutions--normal saline, soapsuds, or vinegar (neutral, alkaline, or acidic solutions, respectively)--to three groups of rabbits (n = 20 per group). The solutions were standardized for volume and temperature and the soapsuds and vinegar solutions were adjusted to be isotonic with normal saline or deionized water. We also included a control group (n = 20) in which the enema tubes were inserted but no solution was administered. We biopsied 3 sites (rectum and distal and proximal colon). Damage to intestinal mucosa was observed by light microscopy and transmission electron microscopy. In order to explore the detection of damage using noninvasive methods, cyclooxygenase (COX)-2 gene expression was measured in the exfoliated cells gathered from postenema defecation. Epithelial loss, inflammatory reaction, and cellular microstructure damage was increased in the vinegar and soapsuds groups. Also, exfoliated cells in these groups had higher COX-2 expression than the normal saline group. The acidic and alkaline enema solutions thus caused more severe damage to the intestinal mucosa compared to the neutral liquid, supporting our hypothesis. Further, the detection of COX-2 expression shows promise as a noninvasive method for estimating enema-induced damage.

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Colorectal Cancer Screening by Double Contrast Barium Enema in Thai People

Cited by 10 publications

References 24 publications

Nanotechnology in Colorectal Cancer for Precision Diagnosis and Therapy

Nanotechnology in Colorectal Cancer for Precision Diagnosis and Therapy

Feasibility of Computed Tomography Colonography as a Diagnostic Procedure in Colon Cancer Screening in India

Relationship Between the pH of Enema Solutions and Intestinal Damage in Rabbits

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