Colorectal cancer outcomes determined by mode of presentation: analysis of population data in England between 2010 and 2014

Franklyn, Joshua; Lomax, Joe; Labib, Peter; Baker, Amy; Hosking, Joanne; Moran, Brendan; Smolarek, Sebastian

doi:10.1007/s10151-022-02574-4

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…The presentation of the disease and the decision of the type of surgical and oncological approach depend on the time of diagnosis or severity of the cancer manifestation; as reported by Franklyn et al 31 on the frequency of emergency first contact presentation among undiagnosed cancer patients living in remote areas, compared to control groups (27.7% vs. 19.7%, p < 0.01) 31 . In this order of ideas, the results obtained in this study are congruent with the conditions under which the patients were evaluated, and differ slightly in some aspects, which are typical of the progress in public policies and programs for early detection and specialized management of colorectal cancer, established in high‐income countries.…”

Section: Discussionmentioning

confidence: 99%

Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital

et al. 2022

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Introduction Colorectal cancer is the most common malignant neoplasm of the gastrointestinal tract. Its incidence and mortality vary markedly at a global level. Assessing the epidemiological behavior of this condition allows reevaluating diagnostic, therapeutic and prognostic options, based on new findings. In Colombia, few studies have correlated variables associated with surgical and oncological outcomes in this type of cancer. Then, the aim of this study was to evaluate the surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean Population. Methods Retrospective cross‐sectional study, including patients with a histopathological diagnosis of colorectal cancer who underwent open or laparoscopic surgery, during a period of two years (2018–2020), from a regional referral hospital. Clinical history variables were collected. Frequencies and prevalence ratios were calculated. Results A total of 84 patients were finally included. Adenocarcinoma of non‐special type with advanced clinical stages was the most prevalent (72.6%). Rectal neoplasia (45.2%) was the most frequent anatomical subsite, followed by proximal colon (p = 0.026). The anatomical subsite of the neoplasm, intraoperative complication (PR 1.38; 95% CI, 1.21–1.59, p = 0.001) and intensive care stay (PR 1.062; 95% CI, 1.01–1.12, p = 0.048) were associated with postoperative outcome. Conclusions The anatomical subsite of the neoplasm location, the presence of intraoperative complications and the stay in intensive care may be associated with the surgical and oncological outcome of individuals with colon cancer from the Colombian Caribbean region.

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Section: Discussionmentioning

confidence: 99%