Colorectal cancer in the Ukraine: analysis and statistical data

Galaychuk, I. Y.; Braun, Eduardo; Voikshnaras, H.

doi:10.1016/s0748-7983(95)92483-3

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Access to treatment is limited due to the significant financial burden placed on patients through high out‐of‐pocket costs and limited funding for health care [3, 5, 8, 9]. With the lack of a CRC screening program and the financial burden associated with treatment, it is not surprising that nearly three quarters of colon cancer patients and two‐thirds of rectal cancer patients present with stage 3 or stage 4 disease [5, 10].…”

Section: Introductionmentioning

confidence: 99%

Colonoscopy Needs for Implementation of a Colorectal Cancer Screening Program in Ukraine

Welten

Wanis²,

Semeniv³

et al. 2022

World j. surg.

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Background In Ukraine, there is no established colorectal cancer screening program. We aimed to project the number of screening colonoscopies needed for implementation of various CRC screening strategies in Ukraine. Methods We modified a previously developed Markov microsimulation model to reflect the natural history of adenoma and CRC progression among average-risk 50-74-year-olds. We simulated colonoscopies needed for the following screening strategies: no screening, fecal occult blood test yearly, FOBT yearly with flexible sigmoidoscopy every 5 years, FS every 5 years, fecal immunohistochemistry test (FIT) yearly, or colonoscopy every 10 years. Assuming 80% screening adherence, we estimated colonoscopies required at 1 and 5 years depending on the implementation rate. In one-way sensitivity analyses, we varied implementation rate, screening adherence, sensitivity, and specificity. Results Assuming an 80% screening adherence and complete implementation (100%), besides a no screening strategy, the fewest screening colonoscopies are needed with an FOBT program, requiring on average 6,600 and 26,800 colonoscopies per 100,000 persons at 1 and 5 years post-implementation, respectively. The most screening colonoscopies are required with a colonoscopy program, requiring on average 76,600 and 101,000 colonoscopies per 100,000 persons at 1 and 5 years post-implementation, respectively. In sensitivity analyses, the biggest driver of number of colonoscopies needed was screening adherence. Conclusions The number of colonoscopies needed and therefore the potential strain on the healthcare system vary substantially by screening test. These findings can provide valuable information for stakeholders on equipment needs when implementing a national screening program in Ukraine.

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