Colorectal Cancer in People with Intellectual Disabilities

Willis, Diane; Samalin, Emmanuelle; Satge, D

doi:10.1159/000492077

Cited by 19 publications

(22 citation statements)

References 64 publications

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“…This may be influenced by gastrointestinal tract dysfunction, gastro-oesophageal reflux disease and chronic constipation which are common in people with intellectual disabilities 28. There is also a suggestion that a higher incidence of these cancers in adults with intellectual disabilities, compared with the general population, may be associated with genetic deletions and family history, being overweight, inactive or having poor nutrition 29. A greater awareness of this among support staff and health professionals is important so that preventative measures can be instigated such as caregivers being vigilant about bowel habits and implementing interventions to increase fibre intake and exercise in daily activities 29…”

Section: Discussionmentioning

confidence: 99%

Cancer in deceased adults with intellectual disabilities: English population-based study using linked data from three sources

et al. 2022

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ObjectiveTo improve our understanding of cancer in adults with intellectual disabilities.DesignPopulation-based study using linked data about deceased adults from the Learning (Intellectual) Disabilities Mortality Review (LeDeR) programme, the national cancer registry and NHS Digital.SettingEngland.Participants1096 adults with intellectual disabilities identified by the LeDeR programme who died between 1 January 2017 and 31 December 2019.Outcome measureAny form of cancer listed as a long-term health condition by a LeDeR reviewer or 10th edition of the International Classification of Diseases codes C00–D49 included on Parts I or II of the Medical Certificate of Cause of Death.ResultsIn decedents with intellectual disabilities and cancer, more than a third (35%; n=162) had cancer diagnosed via emergency presentations. Almost half (45%; n=228) of cancers were at stage IV when diagnosed. More than a third (36%; n=309) of underlying causes of deaths were of cancers of the digestive system; almost half of these (48%; n=147) were cancer of the colon, rectum or anus. Of those who died with colorectal cancer, 43% were below the age threshold for colorectal screening.ConclusionsIn decedents with intellectual disabilities, symptoms suggestive of cancer had tended to be identified most frequently as an emergency and at a late stage. There is a need for greater awareness of symptoms of cancer in this population, a lower threshold for referral by General Practitioners (GPs), accelerated access to diagnosis and treatment and consideration paid to lowering the age for colorectal screening.

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Section: Discussionmentioning

confidence: 99%

Cancer in deceased adults with intellectual disabilities: English population-based study using linked data from three sources

et al. 2022

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“…9 A review on colorectal cancer in people with intellectual disabilities concluded that, although this group has a risk of colorectal cancer comparable with the general population, their uptake of screening is lower. 4 A centrally organized screening program is unable to identify which individuals of the target population have a disability. Future research should explore why the uptake of cancer screening among Flemish disabled persons is lower than the Flemish average.…”

Section: Discussionmentioning

confidence: 99%

“…Although their cancer risk equals that of the general population. 3,4 The objective of this study was to explore the association between different disabilities and participation in cancer screening in Flanders.…”

Section: Introductionmentioning

confidence: 99%

Uptake of cancer screening among adults with disabilities in Flanders (Belgium)

Kellen¹,

Nuyens

Molleman³

et al. 2019

J Med Screen

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Objective To explore the association between disability and participation in breast, cervical, and colorectal cancer screening in Flanders (Belgium). Methods Data from the Centre for Cancer Detection were linked to data of the Flemish Agency for disabled persons by the Crossroads Bank for Social Security, using National Social Security Numbers. Results The study population consisted of 92,334 invited individuals registered as disabled in 2013–2015. For breast cancer screening (including both opportunistic screening and participation in the screening program), 51.7% of disabled women had undergone mammography in the last two years, compared with the Flemish uptake of 61.8%. In cervical screening, 45% of the women with a disability had undergone a PAP smear in the last three years (overall Flemish uptake was 60.7%). For colorectal cancer screening, 40.7% of individuals with a disability had undergone a fecal immunochemical test in the last two years (overall Flemish uptake was 51.5%). Participation in breast and colorectal cancer screening among persons with a disability was 10% points less than the Flemish average during the same period. In the cervical cancer screening program, the difference between the participation of disabled women and the Flemish average was 10% points. Persons with any type of disability had a lower uptake of cancer screening than the Flemish average, except for individuals with a hearing impairment. Conclusions Participation disparities in the Flemish cancer screening programs between persons with and without disabilities require specific efforts to increase cancer screening among people with a disability.

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“…Additionally, they reported statistically significant associations for cancers of the digestive system and intellectual disability 21 . Proposed mechanisms for this association include the role of multiple‐system congenital anomalies 22 and extrinsic factors, such as lack of fiber intake and low physical exercise 23 …”

Section: Discussionmentioning

confidence: 99%