Colorectal Cancer and Common Psychiatric Disorders: A Two-sample Mendelian Randomization Study
Yuan Yao,
Mingze Yang,
Chen Li
et al.
Abstract:Objective: This study aimed to elucidate the causal relationships between colorectal cancer (CRC) and prevalent psychiatric disorders using a two-sample Mendelian randomization approach and to provide evidence supporting the gut-brain axis (GBA) hypothesis.
Methods: Utilizing publicly available GWAS datasets, we explored the connections between CRC and various psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. We applied three statistical analyses: inverse variance weigh… Show more
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