Color Stability of Tablet Formulations III

Light Stability of Norethindrone and Ethinyl Estradiol Formulated with FD&C Colorants

“…In the tablets containing the red dye, the entire tablet discolored, as opposed to the conventional type of' light sensitivity that leads to a surface fading only (3)(4)(5). wt.…”

Rapid Determination of Color Stability of Tablet Formulations

“…A fraction which deposited crystals on evaporation of an aqueous solution has now been obtained, and the active substance, now essentially pure, is being named "stoichactin." This drug was evaluated During a rather broad study of pharmacological activity of over 1000 species of natural products from the Pacific basin, it was found that a number of extrkcts 1 Collected from the reef of Arue Bay in Tahiti by Dr. Frank Tabrah. Dr. Cadet Hand, Director of the University of California Bode a Marine Laboratory, identified this sea anemone as definitely being in 18, genus Sroichuctis and most probably as thc species S. kenfi.…”

Stability of Certified Dyes in Tablets I

“…Previous attempts t o correlate the fading of tablets at different intensities of the incident light have not been satisfactory. Each intensity was considered a separate case and different kinetic constants were calculated for each intensity (3,4). However, since fading is proportional to the product of time, t , and intensity, I (13), plots of Ot DS.…”