Color Doppler velocity profile assessment of portal hemodynamics in cirrhotic patients with portal hypertension: Correlation with esophageal variceal bleeding

Yin, Xiaoyu; Lü, Ming-De; Huang, Jiefu; Xie, Xiaoyan; Liu, Liang

doi:10.1002/1097-0096(200101)29:1<7::aid-jcu2>3.0.co;2-v

Cited by 38 publications

(26 citation statements)

References 18 publications

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“…No simple noninvasive method which accurately predicts esophageal variceal bleeding is available so far and endoscopists have had to perform endoscopy every 3 to 6 mo to evaluate patients with previously bleeding esophageal varices [5,6] . However, this approach is costly and not all patients with liver cirrhosis and esophageal varices are good candidates for such procedures [7] .…”

Section: Introductionmentioning

confidence: 99%

Per rectal portal scintigraphy as a useful tool for predicting esophageal variceal bleeding in cirrhotic patients

Chitapanarux¹

2007

WJG

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AIM:To investigate potential roles of per rectal portal scintigraphy in diagnosis of esophageal varices and predicting the risk of bleeding. METHODS:Fifteen normal subjects and fifty cirrhotic patients with endoscopically confirmed esophageal varices were included. Patients were categorized into bleeder and non-bleeder groups according to history of variceal bleeding. All had completed per rectal portal scintigraphy using 99m Technetium pertechnetate. The shunt index was calculated from the ratio of 99m Technetium pertechnetate in the heart and the liver. Data were analyzed using Student's t -test and receiver operating characteristics. RESULTS:

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Section: Introductionmentioning

confidence: 99%

Per rectal portal scintigraphy as a useful tool for predicting esophageal variceal bleeding in cirrhotic patients

Chitapanarux¹

2007

WJG

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“…However, it was not shown that it is superior to portal vein in detecting the presence of esophageal varices. Similarly, the ratio of splenic vein flow volume to portal trunk flow volume (SV/PT) may be valuable in predicting esophageal variceal bleed [21]. Liver vascular index, calculated as the ratio of portal venous velocity to hepatic artery pulsatility index, has also been shown to be useful in the diagnosis of portal hypertension [22].…”

Section: Resultsmentioning

confidence: 99%

Portal Vein Doppler: A Tool for Non-Invasive Prediction of Esophageal Varices in Cirrhosis

Shastri

Kulkarni

Patell

et al. 2014

JCDR

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Background and Objectives: Esophageal varices (EV), a major complication of liver cirrhosis, can lead to life threatening gastrointestinal (GI) bleeding. Esophagogastroduodenoscopy (EGD) is the gold standard for diagnosis and management of esophageal varices. However, it is not always available in resourceconstrained settings.This study was aimed at evaluating portal vein indices (PVI) using Doppler on ultrasound abdomen, which is more widely available, as tools to predict the presence of EV.

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“…Bolongesi et al [34] and Yen et al [35]demonstrated that the diameters of portal vein and splenic vein were the key criteria for diagnosis of PHT and that there was a linear correlation between the diameters and severity of PHT. However Li et al [36] reported that the diameter of PV and SV were not sensitive enough to be used as markers of PHT severity.…”

Section: Discussion:-mentioning

confidence: 99%

Large Silent Gastric Fundal Varices in Cirrhotic Patients: Role of Abdominal Multidetector Triphasic Computed Tomography.

MD¹,

MD²

2016

IJAR

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Background:-Gastric varices have been recognized as a major cause of gastrointestinal bleeding, reaching 33% in patients with portal hypertension mostly secondary to liver cirrhosis. Compared with esophageal variceal bleeding, haemorrhage caused by fundal varices, although less frequent, is more severe and haemostatic control is more difficult. The diagnosis and treatment of gastrointestinal bleeding are based mainly on endoscopic examinations however; radiological studies such as computed tomography (CT) studies have proved useful in clinical practice. Spiral imaging has dramatically improved CT in the evaluation of focal hepatic lesion. The aim of this study is to investigate the role of abdominal Multidetector triphasic CT scan done for early detection of hepatocellular carcinoma (HCC) as a predictor and diagnostic tool for silent large gastric fundal varices in patients with liver cirrhosis. Methods:-A total of 145 patients were enrolled in this study. All patients were referred for early detection of HCC with suspected focal hepatic lesion or elevated α fetoprotein above 50 and below 400 IU/dl. All patients underwent full clinical and laboratory investigations. Abdominal US was performed for all patients. Abdominal Multidetector triphasic CT scan was done by a single experienced radiologist for evaluation for the presence of hypervascular focal hepatic lesions, splenomegaly, epigastric and hilar collaterals, portal vein thrombosis and the presence of esophageal or gastric fundal varices. All patients underwent standard upper GIT endoscopy and according to the endoscopic findings the studied patients were further classified to three groups: group I (GI) 79 patients (54.48%) with no or small esophageal and/or gastric varices, group II (GII) 42 patients (28.97%) with large esophageal varices, and group III (GIII) 24 patients (16.55%) with large gastric fundal varices Results:-There was a statistically significant increase in portal vein diameter, splenic size (long axis span), splenic vein diameter, presence of gastro-renal collaterals, portal vein thrombosis and HCC in patients with large gastric fundal varices in relation to other groups. platelet/splenic ratio as calculated by dividing platelet count over long axis of the spleen was determined for each patient which had significant lower values in relation to presence of large gastric varicesStep-wise regression analysis was done for all the above mentioned variables revealing that only three predictors namely the presence of large fundal varices by abdominal CT, presence of splenic hilar or splenorenal collaterals and platelet/splenic ratio were found to have highly significant independent ISSN 2320-5407

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Color Doppler velocity profile assessment of portal hemodynamics in cirrhotic patients with portal hypertension: Correlation with esophageal variceal bleeding

Cited by 38 publications

References 18 publications

Per rectal portal scintigraphy as a useful tool for predicting esophageal variceal bleeding in cirrhotic patients

Per rectal portal scintigraphy as a useful tool for predicting esophageal variceal bleeding in cirrhotic patients

Portal Vein Doppler: A Tool for Non-Invasive Prediction of Esophageal Varices in Cirrhosis

Large Silent Gastric Fundal Varices in Cirrhotic Patients: Role of Abdominal Multidetector Triphasic Computed Tomography.

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