Colonoscopic polypectomy in a regional teaching hospital

Minopoulos, Georgios; McIntyre, Richard; Lee, E. C. G.; Kettlewell, M. G. W.

doi:10.1002/bjs.1800700120

Cited by 5 publications

(1 citation statement)

References 9 publications

(9 reference statements)

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“…However, the overall rate of invasive cancer diagnosed in polyps excised colonoscopically is in the range of 4 to 5%. [12][13][14][15][16] In addition to dysplasia, the diagnosis of invasive carcinoma requires the presence of neoplastic cells penetrating the muscularis mucosa.…”

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confidence: 99%

Polyp Histology and Management

Hellinger¹

2002

Clinics in Colon and Rectal Surgery

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A polyp represents a growth of tissue projecting from the surface of the bowel mucosa. Polyps may be neoplastic or non-neoplastic. The only definitive way to determine the type of polyp is with endoscopic sampling. Because there is a high rate of synchronous polyps, total colonoscopy must be performed. Although the vast majority of adenomas are benign, as they grow their malignant potential increases. In fact some of these polyps are found to harbor cancer. The mainstay of therapy therefore is endoscopic excision. Fewer than 5% of polyps are irretrievable colonoscopically. For these polyps, various surgical options are available. The advent of laparoscopic techniques has made surgical intervention much less invasive, especially when combining both laparoscopy and endoscopy. Medical therapy has focused on polyp prevention. However, treatment with nonsteroidal anti-inflammatory drugs, especially COX-2 inhibitors, has been shown to be effective in inducing polyp regression and inhibiting polyp growth.Objectives: Upon completion of this article the reader should be able to summarize the histological subtypes of sporadic colorectal polyps and their clinical significance and management.

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confidence: 99%

Polyp Histology and Management

Hellinger¹

2002

Clinics in Colon and Rectal Surgery

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Frequency of Isolated Proximal Colonic Polyps Among Patients Referred for Colonoscopy

Lieberman

Smith

1988

Arch Intern Med

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Screening of colorectal cancer

Bader

1986

Digest Dis Sci

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Colorectal cancer (CRC) remains a cancer in a disappointing location. However, its location clearly has an advantage that could theoretically permit efficient secondary prevention: the preceding of the cancer by a benign lesion, ie, the adenoma. Complete colonoscopy and its substitute, the double-contrast barium enema, and their specific limitations, must be reserved for high-risk patients: hereditary cancers and ulcerative colitis. For all the others, ie, adults of 45 years of age and with standard risks, the proposal is either to select the patients to be colonoscoped through occult blood testing of the stools or to perform a fiber sigmoidoscopy or a combination of both. Although imperfect, both methods allow the detection of polyps and cancers at a presymptomatic stage, when they are either benign or malignant, but localized and with a better prognosis. However, the absolute proof of the benefits of this strategy of screening would be the demonstration by controlled studies of a prolonged survival rate or a decrease in morbidity. Until now, this proof is not fully available.

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Colonoscopic polypectomy in a regional teaching hospital

Cited by 5 publications

References 9 publications

Polyp Histology and Management

Polyp Histology and Management

Frequency of Isolated Proximal Colonic Polyps Among Patients Referred for Colonoscopy

Screening of colorectal cancer

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