2016
DOI: 10.1093/jac/dkw216
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Colonization with third-generation cephalosporin-resistant Enterobacteriaceae on hospital admission: prevalence and risk factors

Abstract: To our knowledge, this is the largest admission prevalence study of 3GCREB in Europe. The observed prevalence of 9.5% 3GCREB carriage was higher than previously reported and differed significantly among centres. In addition to previously identified risk factors, the treatment of GERD proved to be an independent risk factor for 3GCREB colonization.

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Cited by 85 publications
(94 citation statements)
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“…However, in Germany the prevalence of carbapenemase-producing organisms is still very low. In a recent multicenter study of 4,376 patients, rectal carriage strains carrying VIM-1, NDM-1, and IMP-8 were detected in only 0.11% of patients on admission (25). Nevertheless, we are confident that the current study represents a fairly realistic and comprehensive picture of the epidemiology in the region studied, as the participating laboratories (including the reference center) provide microbiological services for large parts of the region in which GIM-1 has been detected and where a strict program for molecular screening for carbapenemases has been established.…”
Section: Discussionmentioning
confidence: 95%
“…However, in Germany the prevalence of carbapenemase-producing organisms is still very low. In a recent multicenter study of 4,376 patients, rectal carriage strains carrying VIM-1, NDM-1, and IMP-8 were detected in only 0.11% of patients on admission (25). Nevertheless, we are confident that the current study represents a fairly realistic and comprehensive picture of the epidemiology in the region studied, as the participating laboratories (including the reference center) provide microbiological services for large parts of the region in which GIM-1 has been detected and where a strict program for molecular screening for carbapenemases has been established.…”
Section: Discussionmentioning
confidence: 95%
“…Das Vorkommen von 4MRGN war mit 2 Nachweisen und somit einer Gesamtprävalenz von 0,1 % sehr gering. Hamprecht et al gaben in ihrer Studie unter Patienten in 6 Krankenhäusern in Deutschland eine vergleichbare Prävalenz von 0,11 % an [16].…”
Section: Diskussionunclassified
“…Es gibt umschriebene Daten zu nosokomialen Infektionen auf pädiatrischen Intensivstationen (ITS), die mittels des Krankenhaus-Infektions-Surveillance-Systems (KISS) des Nationalen Referenzzentrums für Surveillance von nosokomialen Infektionen erhoben werden [9]. Studien zur Prävalenz und Inzidenz von Infektionen durch multiresistente gramnegative Bakterien auf pädiatrischen Normalstationen (vergleichbar zu der Antibiotika-Therapie-Optimierungsstudie ATHOS bei Erwachsenen) fehlen jedoch bislang in Deutschland [10]. Noch viel seltener sind Untersuchungen zur Prävalenz von MRE in der pädiatrischen ambulanten medizinischen Versorgung, z.…”
Section: Merkeunclassified
“…Der ESBL-Genotyp CTX-M hat sich inzwischen bei Erwachsenen und Kindern in Asien, Europa, Kanada und USA erfolgreich in E. coli und Klebsiella spp. verbreitet und wird inzwischen auch häufiger in Isolaten aus der Bevölkerung und bei ambulant behandelten Patienten nachgewiesen [10,24,25].…”
Section: Merkeunclassified
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