Colonization of the vagina by fungi of the genus Mucor

Zygomycetes in Human Disease

“…Cokeromyces is likewise monotypic. Cokeromyces recurvatus is an unusual clinical isolate which can colonize the human colon and genitourinary tract (13,25,232,289,387). Syncephalastrum racemosum and Mortierella wolfii are two zygomycete isolates whose designations as human pathogens are tenuous.…”

“…They require no light for growth (251,503). Dimorphic conversion has been identified in some species (25,30,289,363,387,443).…”

“…Branching of the hyphae is seen, with wide-angle (generally around 90°) bifurcations noted. Yeast formation (blastoconidial formation) has been observed with Cokeromyces recurvatus, which presents as budding yeast that may be confused with Paracoccidioides braziliensis (102,289,387). In addition, some Mucor species are dimorphic, producing budding yeast at 37°C (443).…”

“…An additional soil isolate was obtained in Texas. All cases of human colonization or infection have occurred in the United States (13,25,232,289,314,387,390,467).…”

Cokeromyces recurvatus infection in a bone marrow transplant recipient

“…There are two reports of C. recurvatus infection successfully treated with amphotericin-B and terconazole, respectively. 4,5 A third case of C. recurvatus was described as vaginal colonization 6 and a fourth case was thought to be vaginal/endocervical colonization. 7 In conclusion, we report a case of Cokeromyces recurvatus infection in a transplant recipient.…”