Colonic preparation with picolax: Patient tolerance and approaches to fluid replacement

Randomized clinical trial of intravenous fluid replacement during bowel preparation for surgery

“…Although there was a shorter length of stay in the outpatient group, these patients also had increased perioperative and postoperative¯uid requirements. In a prospective randomized study Lawrance et al 6 studied ®ve different oral¯uid regimens in 197 patients and found no difference in any of the groups with regard to adverse events. Hill et al 7 demonstrated that patients with cellular potassium depletion were at risk of hypokalaemia after bowel preparation with sodium phosphate.…”

Polyethylene glycol vs sodium picosulfate/magnesium citrate for colonoscopy preparation

“…Magnesium citrate is an osmotically active laxative, which draws fluid into the gut lumen and partly stimulates peristalsis by release of cholecystokinin. Unlike sodium phosphate, products combining sodium picosulfate and magnesium citrate (SPMC) are usually not associated with significant electrolyte disturbances 13 14 15 . The most important concern is the risk of hypermagnesemia in patients with renal failure, as magnesium is eliminated solely by the kidney 15 .…”

Oral Sodium Phosphate (Fleet®) is a Superior Colonoscopy Preparation to Picoprep®(Sodium Picosulfate-Based Preparation)

“…Like any small-volume preparations, side effects, such as nausea, headaches, and abdominal pain, have been reported with picosulfate-magnesium salt combinations. 5,6 The efficacy of various small-volume bowel preparation agents for colonoscopy has not been clearly defined. This single-blinded, randomized trial was designed to compare oral sodium phosphate (Fleet \ ) with Picoprep \ (a sodium picosulfate-based preparation) by evaluating the efficacy in colon cleansing, side effects, and patient acceptability.…”