Colonic mucormycosis in solid organ transplantation: Case report and review of the literature (colonic mucormycosis after DDLT)

Abstract

Mucormycosis is an opportunistic fungal infection that can occur throughout the body and carries a high mortality. Colonic mucormycosis is an uncommon form of the disease whose successful treatment relies upon a high degree of clinical suspicion and early, often empiric, therapy. We report colonic mucormycosis in a liver transplant patient and review the literature on colonic mucormycosis in solid organ transplant recipients.

Gastrointestinal mucormycosis following liver transplantation: lessons learnt

“…If the primary source is detected elsewhere, debridement of the relevant area should be performed. Antifungal therapy should be initiated immediately and immunosuppression reduced when mucormycosis is suspected 5 11 12. The first-line agent includes the lipid formulation of amphotericin B deoxycholate, a polyene antifungal agent 1 2 4–7.…”

An unusual opportunistic infection causing lower gastrointestinal tract bleeding in a patient with severe alcoholic hepatitis, post‐liver transplantation

“…This highly invasive fungal infection is caused by the inhalation or inoculation of Mucorales spores, with the most common presentations being a rhino‐sino‐orbital and pulmonary disease. Surgical site and gastrointestinal mucormycosis is a rare but potentially lethal fungal infection in the post‐transplant setting 2–5 …”

“…Surgical site and gastrointestinal mucormycosis is a rare but potentially lethal fungal infection in the post-transplant setting. [2][3][4][5] We report a case of a 46-year-old man who presented with a history of gradually progressive jaundice, ascites, and grade-1 hepatic encephalopathy (HE). Informed consent was obtained from the patient's relatives for case publication.…”