Colonic metastasis from primary lung adenocarcinoma: a case report and review of the literature

Symptomatic Colonic Metastasis in a Patient with Non-Small Cell Lung Carcinoma

“…Most GI tract metastases are asymptomatic, thus diagnosed postmortem. 2 Symptoms when present may include weight loss, abdominal pain, constipation, diarrhea, and bloody stool. In our case, the patient was diagnosed with colonic metastasis after she presented with melena.…”

“…A significant number of patients that present with NSCLC have distant metastases at the time of diagnosis, however, only a small percentage have abdominal metastasis. 1 , 2 …”

“… 4 , 5 Colonic metastasis often is not diagnosed during life, with up to one-third diagnosed during an autopsy. 2 We present a female with a history of Stage IV NSCLC diagnosed with sigmoid colon metastases after complaints of bright red blood per rectum.…”

“…A significant number of patients that present with NSCLC have distant metastases at the time of diagnosis, however, only a small percentage have abdominal metastasis. 1,2 Abdominal metastases are most often squamous cell carcinoma and can be found in the liver, adrenal glands, pancreas, spleen, kidneys, gastrointestinal (GI) tract, peritoneum, or abdominal lymph nodes. [1][2][3] Metastases to the GI tract are rare with a prevalence rate of 0.5 -14% and are often asymptomatic but can present with abdominal pain, intestinal obstruction, bloody stool, diarrhea, or intestinal perforation.…”

“…1,2 Abdominal metastases are most often squamous cell carcinoma and can be found in the liver, adrenal glands, pancreas, spleen, kidneys, gastrointestinal (GI) tract, peritoneum, or abdominal lymph nodes. [1][2][3] Metastases to the GI tract are rare with a prevalence rate of 0.5 -14% and are often asymptomatic but can present with abdominal pain, intestinal obstruction, bloody stool, diarrhea, or intestinal perforation. 4,5 Colonic metastasis often is not diagnosed during life, with up to onethird diagnosed during an autopsy.…”