Colon Mass as a Secondary Metastasis from Cholangiocarcinoma: A Diagnostic and Therapeutic Dilemma

Abstract

Cholangiocarcinoma (bile ducts cancer) is a rare and aggressive form of cancer. It metastasizes frequently to liver, peritoneum, and lungs. Colon metastasis is extremely uncommon. We report here a 70-year-old male who was diagnosed with cholangiocarcinoma for which he underwent a Whipple procedure. Fifteen months later, a CT scan revealed mural thickening in the colon; this was supplemented with a PET scan, which confirmed this mass. Histological diagnosis of metastatic cholangiocarcinoma to the colon was made and the patient was treated with chemotherapy. Although rare, cholangiocarcinoma metastasis can be found in the colon. A high index of suspicion is required to diagnose and treat early. More cases need to be reported to find out further about the prognosis of the disease.

Metastatic Cholangiocarcinoma Presenting as Colonic Obstruction

“…1 Metastatic spread to the colon is a seldom documented phenomenon, of which we located 10 published case reports. 2–12 Of these, only 2 feature malignant colonic obstruction. 10,13…”

“…1 Metastatic spread to the colon is a seldom documented phenomenon, of which we located 10 published case reports. [2][3][4][5][6][7][8][9][10][11][12] Of these, only 2 feature malignant colonic obstruction. 10,13 Literature describing CCA metastasis features both synchronous and dyssynchronous presentations.…”

A colonic metastasis from extrahepatic cholangiocarcinoma after removal of primary tumor: a case report and literature review

“…Initially, Wakahara reported a male patient with intrahepatic cholangiocarcinoma (ICC) with sigmoidectomy metastasis in 2005 (2). The other six cases were reported in the year of 2010, 2011, 2012, and 2016, respectively (Table 1) (3)(4)(5)(6)(7)(8). The mean age of these patients is 63.6 (range, 57-76).…”