This case study involves a 63-year-old man with a chief complaint of urinary incontinence and pneumaturia. He was treated 2 years ago for prostate cancer with external beam radiation, and most recently with a salvage prostatectomy for local persistent prostate cancer. His symptoms began several weeks after the prostatectomy. He has no other chronic medical problems or past surgical history. His last screening colonoscopy demonstrated diverticulosis, and he has never been treated for diverticulitis. The patient reports frequent and copious passage of fl uid per rectum. He denies fecal incontinence. Figure 1 displays a representative image from a cystogram. What is the diagnosis? What is the next step in the management of this patient? If a surgical intervention is offered, when should it be done? What specifi c techniques should be used? How and when can the urinary incontinence be addressed? Expert Commentary: Drs. Crane and SantucciThe patient described has a constellation of symptoms worrisome for a colovesical fi stula. One must have a very high index of suspicion in a patient with a recent history of prostatectomy presenting with the combination of pneumaturia and passage of fl uid per rectum. Complicating factors include the history of radiation and diverticulitis. Urinary incontinence in the fi rst few months after a prostatectomy is not abnormal and would not necessarily raise concern. Cystogram is the defi nitive study to make the diagnosis; however, a cystoscopy with bilateral retrogrades also is indicated to rule out ureteral involvement and to fully understand the anatomy. Timing of repair is controversial. Most reconstructive urologists would not repair this until at least 6 weeks had passed from the last surgery. Many would wait much longer-at least 3 to 4 months. Some plastic surgeons with experience in this fi eld require at least 6 months before repair is contemplated.Once the diagnosis is made, the success of nonoperative treatments is dependent on the time course of fi stula occurrence and the size of the fi stula. If it is early and the fi stula is small, fulguration of the fi stula with urinary diversion via a suprapubic tube is worth a 6-week trial, although we admit that few fi stulas respond to this treatment. Because of the history of radiation, we believe this approach is even less likely to succeed. Also, a patient with a late fi stula occurrence has a lower probability of success. Scattered case reports on the use of fi brin glue on small colovesical and vesicovaginal fi stulae are found in the literature. In a review by Shekarriz and Stoller [1] on the use of fi brin sealants in urology, the authors commented that the results have been satisfactory. This is based, however, on a small number of case reports; therefore, general recommendations should be made, and treatments should be individualized. Our experience is that unless the fi stula is small in diameter and long enough to hold the fi brin glue plug in place, then fi brin sealants seldom work. We are also pessimistic about any co...