Colloids versus crystalloids for fluid resuscitation in critically ill patients

Perel, Pablo; Roberts, Ian

doi:10.1002/14651858.cd000567.pub5

Cited by 235 publications

(257 citation statements)

References 104 publications

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“…were not recommended [17]. However, survival in our cohort was 100% and this may indicate that mortality during the initial period of resuscitation may not be a sensitive outcome for the importance of colloids and specifically, albumin.…”

Section: Discussionmentioning

confidence: 62%

“…albumin or hypertonic saline is controversial. Albumin for example is more expensive and a meta analysis of 24 trials involving 9920 patients demonstrates that it fails to improve survival when compared with crystalloids [17]. Similarly, hypertonic crystalloid saline has been associated with renal failure and death in one observational study and seems to offer no added benefit to isotonic solutions [18] [19].…”

Section: Introductionmentioning

confidence: 99%

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Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Habib¹,

Saadah²,

Al-Samerrae³

et al. 2017

MPS

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Objective: Evaluation of the effect of Ringer Lactate, as the resuscitative burn fluid according to Parkland Formula, on restoring the levels of body electrolytes and proteins. Design: A retrospective cohort study. Setting: The National Burns Unit, Mafraq Hospital, Abu Dhabi, United Arab Emirates (UAE). Patients: One hundred and fifteen patients admitted with fresh burns between 1st of January 2011 and 31st of December 2013, who met inclusion and exclusion criteria. Methods: Team collected demographic and clinical data for each patient using a standard form. Patients received Ringer Lactate solely as the resuscitative burn fluid according to Parkland Formula. Baseline (pre-) and third-day (post-) variables included levels of sodium, potassium, chloride, proteins, and albumin. Researchers then performed paired comparisons of serum electrolytes and protein levels. Results: Mean values showed maintenance of the potassium and chloride levels within the normal range after administering the Ringer Lactate, significant decline in sodium, and a marked hypoproteinaemia and hypoalbuminaemia post-resuscitation. Conclusions: Ringer Lactate used as the mere resuscitative post burn fluid is suboptimal. Sodium supplementation may be required to correct hyponatremia. Colloids, preferably intravenous albumin should be added, as advised by the original Parkland Formula.

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Section: Discussionmentioning

confidence: 62%

Section: Introductionmentioning

confidence: 99%

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Habib¹,

Saadah²,

Al-Samerrae³

et al. 2017

MPS

View full text Add to dashboard Cite

show abstract

“…Few RCTs studied the type of fluids. In critically ill patients in general, colloids are discouraged since there is no evidence to support their effectiveness whereas hydroxyethyl starch might even increase mortality 11. The IAP/APA guideline therefore proposes crystalloids in the form of Ringer’s lactate.…”

Section: Early Phase Of Acute Pancreatitismentioning

confidence: 99%

Acute pancreatitis: recent advances through randomised trials

Dijk¹,

Hallensleben

Santvoort³

et al. 2017

Gut

346

243

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Acute pancreatitis is one of the most common GI conditions requiring acute hospitalisation and has a rising incidence. In recent years, important insights on the management of acute pancreatitis have been obtained through numerous randomised controlled trials. Based on this evidence, the treatment of acute pancreatitis has gradually developed towards a tailored, multidisciplinary effort, with distinctive roles for gastroenterologists, radiologists and surgeons. This review summarises how to diagnose, classify and manage patients with acute pancreatitis, emphasising the evidence obtained through randomised controlled trials.

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“…The analysis found no significant differences in outcomes (rate of infection, length of hospital stay, mortality) when colloid was compared with crystalloid in patients who had experienced trauma or burns, or who were undergoing major abdominal surgery. In 2007, additional studies were added to the meta-analysis, 14 and again there were no significant differences in outcomes.…”

Section: Fluid Infusionmentioning

confidence: 99%

Resuscitation of Combat Casualties

Marshall

2010

AACN Advanced Critical Care

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Resuscitation and trauma anesthesia of combat casualties is very similar to trauma care in any US hospital--except for the setting. Using case examples, this article describes the principles of trauma anesthesia and resuscitation and the lessons learned regarding the modifications required when caring for a combat casualty. Examples of a massive trauma resuscitation (>10 units of packed red blood cells in 24 hours) and burn resuscitation are presented.

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Colloids versus crystalloids for fluid resuscitation in critically ill patients

Abstract: Analysis 02.01. Comparison 02 colloid and hypertonic crystalloid vs isotonic crystalloid, Outcome 01 deaths. .. Analysis 03.01. Comparison 03 colloid vs hypertonic crystalloid, Outcome 01 deaths. .. .. .. .. . .

Cited by 235 publications

References 104 publications

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Does Ringer Lactate Used in Parkland Formula for Burn Resuscitation Adequately Restore Body Electrolytes and Proteins?

Acute pancreatitis: recent advances through randomised trials

Resuscitation of Combat Casualties

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