1993
DOI: 10.1177/030006059302100406
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Colloidal Silicic Acid for Oral and Topical Treatment of Aged Skin, Fragile Hair and Brittle Nails in Females

Abstract: In an open study, women with biologically aged skin and fragile or thin hair, or brittle nails were treated orally with 10 ml colloidal silicic acid (Silicol) once daily for 90 days and applied colloidal silicic acid to the face for 10 min twice daily. Of the 50 subjects treated, three withdrew from treatment after 30 days because of excessive drying of the facial skin due to topical application. In the remaining 47 subjects there was statistically significant improvement in the thickness and turgor of the ski… Show more

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Cited by 38 publications
(26 citation statements)
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“…We were careful to avoid the latter by using fasting serum and urine samples following a minimum of a 10 h fast and previous data has shown this to be more than adequate [10,14,24]. This marked increase in the body pool of silicon supports the argument that MMST is an effective silicon supplement and also explains why this form of silicon has been shown to positively influence bone and blood vessels in mammalian studies [8,9,11,12] in much the same way that dietary silicon does [1,26,27,30-33]. …”
Section: Discussionsupporting
confidence: 77%
See 1 more Smart Citation
“…We were careful to avoid the latter by using fasting serum and urine samples following a minimum of a 10 h fast and previous data has shown this to be more than adequate [10,14,24]. This marked increase in the body pool of silicon supports the argument that MMST is an effective silicon supplement and also explains why this form of silicon has been shown to positively influence bone and blood vessels in mammalian studies [8,9,11,12] in much the same way that dietary silicon does [1,26,27,30-33]. …”
Section: Discussionsupporting
confidence: 77%
“…As a result, sustained low dose silicon supplementation leads to a marked rise in the body pool of silicon [25], presumably as the second, minor pathway is increasingly loaded. The biologically important target sites for dietary and supplemental silicon appear to be the connective tissues, such as blood vessels [9,29], joints, skin [30-32] and, especially, bone [2,8,11,12,26,33]. Thus the increase in fasting serum and urine Si concentrations following MMST supplementation must result from silicon that has entered the metabolic pool and not that which is destined for immediate urinary excretion following absorption.…”
Section: Discussionmentioning
confidence: 99%
“…It was reported that silicon is connected with bone mineralization and osteoporosis [31], collagen synthesis and ageing of skin [11], condition of hair and nails [32], atherosclerosis [33,34], Alzheimer disease [9,35,36], as well as with other biological effects and disorders. Trace minerals are known to generally play a vital role in the human body homeostasis [37] and the serum levels of silicon are similar to other trace elements, i.e.…”
Section: Therapeutic and Biological Effects Of Ortho-silicic Acid Andmentioning
confidence: 99%
“…Data from the literature show that this decrease can affect the synthesis of collagen by the fibroblasts, as well as the activations of dermal collagenase-in this sense, improvement in collagen type I synthesis are one of the alleged benefits of Si supplementation [6]. Additionally, other benefits found in literature are: (i) promotion of the synthesis of elastin; (ii) stimulus for nail hardness; (iii) increase of resistance and thickness of hair fiber; and (iv) preservation of blood vessel elasticity [6][7][8][9][10][11]. These effects are important because skin ageing involves decrease in collagen, glycosaminoglycans and proteoglycans, together with degeneration of elastic fibers [6].…”
Section: Introductionmentioning
confidence: 99%