We study Fermi-liquid properties of a weakly interacting two-dimensional gas of single-component fermionic polar molecules with dipole moments d oriented perpendicularly to the plane of their translational motion. This geometry allows the minimization of inelastic losses due to chemical reactions for reactive molecules and, at the same time, provides a possibility of a clear description of many-body (beyond mean-field) effects. The long-range character of the dipole-dipole repulsive interaction between the molecules, which scales as 1/r 3 at large distances r, makes the problem drastically different from the well-known problem of the two-species Fermi gas with repulsive contact interspecies interaction. We solve the low-energy scattering problem and develop a many-body perturbation theory beyond the mean field. The theory relies on the presence of a small parameter k F r * , where k F is the Fermi momentum and r * = md 2 /h 2 is the dipole-dipole length, with m being the molecule mass. We obtain thermodynamic quantities as a series of expansion up to the second order in k F r * and argue that many-body corrections to the ground-state energy can be identified in experiments with ultracold molecules, as it has been recently done for ultracold fermionic atoms. Moreover, we show that only many-body effects provide the existence of zero sound and calculate the sound velocity.