Collective Cell Radial Ordered Migration in Spatial Confinement
Hao Dong,
Fen Hu,
Xuehe Ma
et al.
Abstract:Collective cells, a typical active matter system, exhibit complex coordinated behaviors fundamental for various developmental and physiological processes. The present work discovers a collective radial ordered migration behavior of NIH3T3 fibroblasts that depends on persistent top‐down regulation with 2D spatial confinement. Remarkably, individual cells move in a weak‐oriented, diffusive‐like rather than strong‐oriented ballistic manner. Despite this, the collective movement is spatiotemporal heterogeneous and… Show more
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