Collagenous colitis and fecal stream diversion

Järnerot, Gunnar; Tysk, Curt; Bohr, Johan; Eriksson, Sara

doi:10.1016/0016-5085(95)90332-1

Cited by 243 publications

(140 citation statements)

References 12 publications

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“…This theory is supported by the observation that diversion of the fecal stream by an ileostomy normalizes or reduces the characteristic histopathological changes in CC [54] . After closure of the ileostomy, recurrence of symptoms and histopathological changes occur.…”

Section: Luminal Factorsmentioning

confidence: 84%

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Diagnosis and management of microscopic colitis

Tysk¹,

Bohr²,

Nyhlin³

et al. 2008

WJG

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Microscopic colitis, comprising collagenous and lymphocytic colitis, is characterized clinically by chronic watery diarrhea, and a macroscopically normal colonic mucosa where diagnostic histopathological features are seen on microscopic examination. The annual incidence of each disorder is 4-6/100 000 inhabitants, with a peak incidence in 60-70-year-old individuals and a noticeable female predominance for collagenous colitis. The etiology is unknown. Chronic diarrhea, abdominal pain, weight loss, fatigue and fecal incontinence are common symptoms, which impair the health-related quality of life of the patient. There is an association with other autoimmune disorders such as celiac disease, diabetes mellitus, thyroid disorders and arthritis. Budesonide is the best-documented shortterm treatment, but the optimal long-term strategy needs further study. The long-term prognosis is good and the risk of complications including colonic cancer is low.

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Section: Luminal Factorsmentioning

confidence: 84%

“…Both split ileostomy and subtotal colectomy have been performed and reported as successful [54,106] . The indications for surgical therapy today are limited, considering the improvement of medical therapy.…”

Section: Therapy and Prognosismentioning

confidence: 99%

Diagnosis and management of microscopic colitis

Tysk¹,

Bohr²,

Nyhlin³

et al. 2008

WJG

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“…Otras opciones terapéuticas, han demostrado su efectividad en series cortas, refractarias al tratamiento con aminosalicilatos y corticoides; entre ellas se incluyen: metronidazol (32) y en casos de diarrea severa, methotrexate, azathioprina, 6-mercaptopurina (33) y octeótrido subcutáneo (34). Solamente en casos de colitis microscópica refractaria al tratamiento médico y con gravedad manifiesta, es necesario emplear la cirugía y concretamente la ileostomía temporal; intervención que en la mayoría de casos no es definitiva, dado que suele producirse una recaída al restablecer la continuidad del tubo digestivo (35).…”

Section: Discussionunclassified

Colitis microscópica: Un diagnóstico a tener en cuenta en caso de diarrea secretora

Guillén

García

Barranco

2004

An. Med. Interna (Madrid)

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“…Diversion of the fecal stream will cause the histologic changes of CC to regress, whereas reestablishing the fecal stream will induce a relapse of both the abnormal collage layer and clinical symptoms. 17 …”

Section: Microscopic Colitis Collagenous Colitismentioning

confidence: 99%

The Differential Diagnosis of Colitis in Endoscopic Biopsy Specimens: A Review Article

Cerilli

Greenson

2012

Archives of Pathology &Amp; Laboratory Medicine

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Context.-A variety of inflammatory disorders may affect the colon, with widely differing clinical outcomes and management. These conditions encompass a spectrum of acute and chronic conditions.Objective.-Review the pathology of the major colitides and highlight the most diagnostically useful features.Data Sources.-Review of recent literature supplemented with personal experience in the field of gastrointestinal pathology.Conclusions.-The etiologies associated with the various types of colitis are diverse and the range of histologic changes is somewhat limited. Nevertheless, the combination of clinical and endoscopic data coupled with histopathology allows for accurate classification in the majority of cases.

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Collagenous colitis and fecal stream diversion

Cited by 243 publications

References 12 publications

Diagnosis and management of microscopic colitis

Diagnosis and management of microscopic colitis

Colitis microscópica: Un diagnóstico a tener en cuenta en caso de diarrea secretora

The Differential Diagnosis of Colitis in Endoscopic Biopsy Specimens: A Review Article

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