Collagenofibrotic glomerulopathy – A rare disease diagnosed with the aid of transmission electron microscopy

Collagen type III is commonly detected in the renal interstitium and vasculature; however, it is absent in healthy glomeruli. Deposition of collagen type III in the glomerular mesangium and capillary basement membranes may arise in two rare diseases, namely collagen type III glomerulopathy (CG) and nail patella syndrome. CG is a rare glomerular disease with no specific treatment, although supportive measures for control of hypertension and edema may help to relieve symptoms. With progression to end-stage renal disease, patients with CG may come to require dialysis and/or renal transplantation. The present study reported on a 59-year-old male who was diagnosed with CG nephrotic syndrome by immunohistochemical and electron microscopic examination of biopsy material. To the best of our knowledge, this is the first case reported in northeastern China. The angiotensin II blocker telmisartan was successfully used to alleviate renal symptoms and a literature review was performed. The present case supports the use of telmisartan as a first choice of treatment for CG.

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Telmisartan alleviates collagen type III glomerulopathy: A case report with literature review

Guo

Liu

Nie

et al. 2020

Exp Ther Med

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Collagenofibrotic glomerulopathy – A rare disease diagnosed with the aid of transmission electron microscopy

Cited by 1 publication

References 9 publications

Telmisartan alleviates collagen type III glomerulopathy: A case report with literature review

Telmisartan alleviates collagen type III glomerulopathy: A case report with literature review

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Collagenofibrotic glomerulopathy – A rare disease diagnosed with the aid of transmission electron microscopy

Cited by 1 publication

References 9 publications

Telmisartan alleviates collagen type&nbsp;III glomerulopathy: A case report with literature review

Telmisartan alleviates collagen type&nbsp;III glomerulopathy: A case report with literature review

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Telmisartan alleviates collagen type III glomerulopathy: A case report with literature review

Telmisartan alleviates collagen type III glomerulopathy: A case report with literature review