Collagen peptide fractions from tilapia (Oreochromis aureus Steindachner, 1864) scales: Chemical characterization and biological activity

Hernández-Ruiz, Karen Lilián; López‐Cervantes, Jaime; Sánchez‐Machado, Dalia I.; Campas‐Baypoli, Olga N.; Quintero-Guerrero, Angie Araí; Grijalva-Delgado, Maria de Lourdes; Chávez-Almanza, Andrés Francisco

doi:10.1016/j.fbio.2023.102658

Cited by 9 publications

(3 citation statements)

References 47 publications

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“…The small differences might be related to the amino acid composition. It was found that the tyrosine concentration of skate cartilage collagen was lower than that of tilapia skin collagen [ 20 , 21 ].…”

Section: Resultsmentioning

confidence: 99%

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Distribution, Typical Structure and Self-Assembly Properties of Collagen from Fish Skin and Bone

Zhang,

Wang,

Zhang

et al. 2023

Molecules

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The source and type of collagen are crucial to its application, and both play a decisive role. Collagen was prepared from both tilapia skin and bone and skate skin and cartilage, named as CI-TI-s, CI-TI-b, CI-SK-s, and CII-SK-c, respectively. Types, distributions, structures, and self-assembly of collagen were studied. It showed that yellow collagen fibers from skin arranged longitudinally, while collagen fibers from skate cartilages displayed varying colors. CI-TI-s, CI-TI-b, CI-SK-s, and CII-SK-c showed the typical amide A (3316–3336 cm−1) and amide B (2929–2948 cm−1) in FTIR spectra. CI-TI-b and CII-SK-c showed 218–229 nm of UV absorption, 11.56–12.20 Å of d values in XRD, and 0.12–0.14 of Rpn values in CD. The thermal denaturation temperatures of CI-TI-s and CI-SK-s were 30.7 and 20.6 °C, respectively. The self-assembly of CI-TI-s and CII-SK-c were maximum at pH 7.2 and 7.4–7.6, respectively. The unique collagen peptides of tilapia and skate were GPSGPQGAVGATGPK, PAMPVPGPMGPMGPR, SPAMPVPGPMGPMGPR, GESGPSGPAGPAGPAGVR, SSGPPVPGPIGPMGPR, GLTGPIGVPGPPGAQGEK, GLAGPQGPR, and GLSGDPGVQGIK, respectively. The unique peptides of type I and type II collagen were GPTGEIGATGLAGAR, GVLGLTGMR, LGLTGMR, GEPGAAGPAGPSGPMGPR, SSGPPVPGPIGPMGPR, and GLSGDPGVQGIK, respectively.

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Section: Resultsmentioning

confidence: 99%

“…The UV absorption peak of collagen 230 nm was related to the n → Π* transition of C=O, COOH, and CO-NH2 group small differences might be related to the amino acid composition. It was foun tyrosine concentration of skate cartilage collagen was lower than that of tilapia s gen [20,21].…”

Section: Analysis Of the Uv Spectra Of Ci-ti-s Ci-ti-b Ci-sk-s And Ci...mentioning

confidence: 87%

Distribution, Typical Structure and Self-Assembly Properties of Collagen from Fish Skin and Bone

Zhang,

Wang,

Zhang

et al. 2023

Molecules

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“…16,17 However, this does not mean the higher degree of hydrolysis would result in higher biological activity of collagen peptide. A medium degree of enzymatic hydrolysis would be appropriate for good antioxidant activity while small peptides are essential to obtain high ACE-inhibitory activity, 18,19 A 5–10 kDa fraction of the collagen peptides obtained would be good tyrosinase and collagenase inhibitors with the best potential antiaging activity. 20 Therefore, the relationship between the degree of hydrolysis and the function of collagen is complex, which needs further research work to explore potential collagen peptides with high physiological activity.…”

Section: Introductionmentioning

confidence: 99%

The targeted development of collagen-active peptides based on composite enzyme hydrolysis: a study on the structure–activity relationship

Hu,

Yang,

Chang

et al. 2024

Food Funct.

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Antioxidant synergistic anti‐inflammatory effect in the MAPK/NF‐κB pathway of peptide KGEYNK (KK‐6) from giant salamander (Andrias davidianus)

Zhan,

Wu,

et al. 2024

J Sci Food Agric

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BACKGROUNDGiant salamander protein peptide is a peptide with rich functional properties. Giant salamander protein peptide KGEYNK (KK‐6) is a peptide with both antioxidant and anti‐inflammatory properties. The antioxidant and anti‐inflammatory mechanisms of KK‐6 are still unclear. When we studied the functional mechanism of KK‐6, we found that the antioxidant property of KK‐6 has a synergistic and promoting effect on anti‐inflammatory properties.RESULTSKK‐6 enhances cellular resistance to LPS via the MAPK/NF‐κB signaling pathway, leading to increased levels of inflammatory factors: interleukin‐1β (764.81 ng mL−1), interleukin‐6 (1.06 ng mL−1) and tumor necrosis factor‐α (4440.45 ng mL−1). KK‐6 demonstrates potent antioxidant properties by activating the Nrf2 signaling pathway, resulting in elevated levels of antioxidant enzymes (glutathione peroxidase: 0.03 μg mL−1; superoxide dismutase: 0.589 μg mL−1) and a reduction in the concentration of the oxidative product malondialdehyde (967.05 μg mL−1).CONCLUSIONOur findings highlight the great potential of KK‐6, a peptide extracted from giant salamander protein, as a remedy for intestinal inflammation. Through its dual role as an antioxidant and anti‐inflammatory agent, KK‐6 offers a promising avenue for alleviating inflammation‐related damage and oxidative stress. This study lays the foundation for further exploration of giant salamander products and highlights their importance in health and novel food development. © 2024 Society of Chemical Industry.

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Collagen peptide fractions from tilapia (Oreochromis aureus Steindachner, 1864) scales: Chemical characterization and biological activity

Cited by 9 publications

References 47 publications

Distribution, Typical Structure and Self-Assembly Properties of Collagen from Fish Skin and Bone

Distribution, Typical Structure and Self-Assembly Properties of Collagen from Fish Skin and Bone

The targeted development of collagen-active peptides based on composite enzyme hydrolysis: a study on the structure–activity relationship

Antioxidant synergistic anti‐inflammatory effect in the MAPK/NF‐κB pathway of peptide KGEYNK (KK‐6) from giant salamander (Andrias davidianus)

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