Collagen from Turkey (Meleagris gallopavo) tendon: A promising sustainable biomaterial for pharmaceutical use

Grønlien, Krister Gjestvang; Pedersen, Mona Elisabeth; Sanden, Karen Wahlstrøm; Høst, Vibeke; Karlsen, Jan; Tønnesen, Hanne

doi:10.1016/j.scp.2019.100166

Cited by 21 publications

(11 citation statements)

References 45 publications

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“…The characteristic band of collagen and chitosan, which is located at a length of 2925 cm -1 , could be related to the asymmetrical stretch of CH [16]. The carbonyl group is also present at 1540 cm -1 ; this group corresponds to the chitosan molecule and amide II band in collagen [17]. The salient absorption bands at around 1020 cm -1 and 1070 cm -1 are identified as the coupled C-C and C-O stretching vibrations, respectively.…”

Section: Molecular Distribution Of Chitosan/triclosan/collagen Matrixesmentioning

confidence: 93%

Biocidal and bioresorbable chitosan/triclosan/collagen matrixes

et al. 2019

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Biomedical application of biomaterials has increased in recent years. Some preferred characteristics of these materials are biocompatibility, biodegradability and antimicrobial effect. We are facing a constant search for antimicrobial materials to be used instead of antibiotics therapy to reduce the possibility of dental surgery contamination. In this study, biocidal, bioresorbable and non-toxic matrixes were synthesized from chitosan, triclosan and collagen. Three experimental groups received different chitosan/collagen combinations, (0.5:1, 0.75:1 and 1:1), all with the same dose of triclosan (0.1%). Antimicrobial effect was measured by the inhibition of S. aureus growth. Moreover, matrixes were placed in a PBS-collagenase solution to measure degradation over time; matrix residues were evaluated at 1, 4, and 7 days. Finally, cell toxicity of each matrix was analyzed on NIH-3T3 fibroblast cells. As a result, inhibition of S. aureus growth was similar in the three established experimental groups of matrixes vs vancomycin antibiotic as control. These data suggest potent antimicrobial effect of chitosan/triclosan/collagen matrixes. Degradation over time showed that 80% of the matrix was degraded after 4 days, thus suggesting that chitosan/triclosan/collagen matrixes are bioresorbable material. On the other hand, viability of NIH-3T3 cells was between 60% to 74% after 24 h and prior to matrix exposition to culture cells. These data indicate light toxicity in the 0.5:1 and 0.75:1 matrix groups and non-toxic effect in the 1:1 matrix group. By taking together these data, we propose the application of chitosan/triclosan/collagen matrixes to prevent bacterial contamination after dental surgery.

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Section: Molecular Distribution Of Chitosan/triclosan/collagen Matrixesmentioning

confidence: 93%

Biocidal and bioresorbable chitosan/triclosan/collagen matrixes

et al. 2019

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“…Collagen type I: Mammalian skin, and tendon tissues (porcine, bovine and ovine in origin); collagen type II: bovine, porcine and chicken cartilaginous tissues [24,44]; marine collagen [45][46][47].…”

Section: Collagenmentioning

confidence: 99%

“…Collagen biomaterials also exhibit potential in drug delivery, having natural biocompatibility as an extracellular matrix protein [ 44 ]. Collagen extracted from turkey tendon, a waste product from the poultry industry, can be formed into sponge scaffolds following gelation, cross-linking and freeze-drying, with prilocaine hydrochloride loaded as a model drug [ 44 ]. Gelatin, formed from the partial hydrolysis of collagen, can similarly form hydrogels for drug delivery applications.…”

Section: Tissue Engineeringmentioning

confidence: 99%

Recent developments in sustainably sourced protein-based biomaterials

Agnieray

Glasson

Chen

et al. 2021

Biochemical Society Transactions

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Research into the development of sustainable biomaterials is increasing in both interest and global importance due to the increasing demand for materials with decreased environmental impact. This research field utilises natural, renewable resources to develop innovative biomaterials. The development of sustainable biomaterials encompasses the entire material life cycle, from desirable traits, and environmental impact from production through to recycling or disposal. The main objective of this review is to provide a comprehensive definition of sustainable biomaterials and to give an overview of the use of natural proteins in biomaterial development. Proteins such as collagen, gelatin, keratin, and silk, are biocompatible, biodegradable, and may form materials with varying properties. Proteins, therefore, provide an intriguing source of biomaterials for numerous applications, including additive manufacturing, nanotechnology, and tissue engineering. We give an insight into current research and future directions in each of these areas, to expand knowledge on the capabilities of sustainably sourced proteins as advanced biomaterials.

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“…A collagen reference sample was extracted from turkey tendons following a literature procedure (Grønlien et al, 2019). A Raman spectrum was recorded from this sample for comparison with Raman spectra from more complex beef and poultry samples.…”

Section: Pure Turkey Collagenmentioning

confidence: 99%

Raman, near-infrared and fluorescence spectroscopy for determination of collagen content in ground meat and poultry by-products

Monago-Maraña

Wold

Rødbotten

et al. 2021

LWT

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Raman, near-infrared and fluorescence spectroscopy were evaluated for determination of collagen content in ground meat. Two sample sets were used (i.e. ground beef and ground poultry byproducts), and collagen concentrations (measured as hydroxyproline) varied in the ranges 0.1-3.3% in the beef samples and 0.4-1.5% in the poultry samples. Similar validation results for hydroxyproline were obtained for NIRS (R 2 = 0.82 and RMSECV = 0.11%) and Raman (R 2 = 0.81 and RMSECV = 0.11%) for the poultry samples. For the beef samples, NIRS obtained slightly less accurate results (R 2 = 0.89, RMSECV= 0.25%) compared to Raman (R 2 = 0.94, RMSECV= 0.19%), most likely due to less representative sampling. Fluorescence spectroscopy gave higher prediction errors (RMSECV= 0.50% and 0.13% for beef and poultry, respectively). This shows that Raman spectroscopy employing a scanning approach for representative sampling is a potential tool for on-line determination of collagen in meat.

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Collagen from Turkey (Meleagris gallopavo) tendon: A promising sustainable biomaterial for pharmaceutical use

Cited by 21 publications

References 45 publications

Biocidal and bioresorbable chitosan/triclosan/collagen matrixes

Biocidal and bioresorbable chitosan/triclosan/collagen matrixes

Recent developments in sustainably sourced protein-based biomaterials

Raman, near-infrared and fluorescence spectroscopy for determination of collagen content in ground meat and poultry by-products

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