Collagen Fibril Diameter and Leather Strength

Wells, Hannah C.; Edmonds, Richard L.; Kirby, Nigel; Hawley, Adrian; Mudie, Stephen; Haverkamp, Richard G.

doi:10.1021/jf4041854

Cited by 47 publications

(37 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Collagen fibril diameter has been shown to have some influence on tissue strength. 11,12 In addition, proteogylcan connections between collagen fibrils in tendon subjected to tensile stress have been suggested as contributing to the strength of the tissue. 13,14 Examination of individual collagen fibrils in rat tail tendon with atomic force microscopy can yield an estimate of the Poisson's ratio measured in compression in a transverse direction.…”

Section: Introductionmentioning

confidence: 99%

Poisson's ratio of collagen fibrils measured by small angle X-ray scattering of strained bovine pericardium

Wells

Sizeland

Kayed

et al. 2015

Journal of Applied Physics

Self Cite

View full text Add to dashboard Cite

Type I collagen is the main structural component of skin, tendons, and skin products, such as leather. Understanding the mechanical performance of collagen fibrils is important for understanding the mechanical performance of the tissues that they make up, while the mechanical properties of bulk tissue are well characterized, less is known about the mechanical behavior of individual collagen fibrils. In this study, bovine pericardium is subjected to strain while small angle X-ray scattering (SAXS) patterns are recorded using synchrotron radiation. The change in d-spacing, which is a measure of fibril extension, and the change in fibril diameter are determined from SAXS. The tissue is strained 0.25 (25%) with a corresponding strain in the collagen fibrils of 0.045 observed. The ratio of collagen fibril width contraction to length extension, or the Poisson's ratio, is 2.1 ± 0.7 for a tissue strain from 0 to 0.25. This Poisson's ratio indicates that the volume of individual collagen fibrils decreases with increasing strain, which is quite unlike most engineering materials. This high Poisson's ratio of individual fibrils may contribute to high Poisson's ratio observed for tissues, contributing to some of the remarkable properties of collagen-based materials.

show abstract

Section: Introductionmentioning

confidence: 99%

Poisson's ratio of collagen fibrils measured by small angle X-ray scattering of strained bovine pericardium

Wells

Sizeland

Kayed

et al. 2015

Journal of Applied Physics

Self Cite

View full text Add to dashboard Cite

show abstract

“…The main component of this hide is collagen, which is a natural polypeptide biopolymer that confers mechanical properties to the hide [1,2]. Among the 26 types of collagens known, the main structural component of animal hide and skin is type I that forms the basic strong fibril [3]. The collagen triple helix of collagen type I is sensitive to UV-254 nm radiation [4].…”

Section: Introductionmentioning

confidence: 99%

Influence of UV radiation on the viscoelastic properties and dynamic viscosity of bovine hide using dynamic mechanical analysis

Nalyanya

Migunde

Ngumbu

et al. 2015

J Therm Anal Calorim

View full text Add to dashboard Cite

The wide range of applications of collagenbased materials has triggered research interest especially on the effect of environmental factors in that these materials are exposed to during processing and application. As the applications of these collagenous materials continue to increase such as in the field of medicine, more studies are required to gain more insight into their properties. Collagen is a natural biopolymer whose structure is sensitive to ultraviolet (UV) radiations, which alters its mechanical properties. In this study, the influence of artificial UV irradiations, wavelength 254 nm, on the viscoelastic properties and dynamic viscosity of both pickled and tanned hide was investigated by dynamic mechanical analysis. The influence of tanning on the viscoelastic properties and dynamic viscosity was also investigated. Freshly flayed bovine hide was conventionally prepared to pickling stage and split into two identical halves along the backline. One half was tanned using chromium sulfate, while the other half was left at the pickled stage. Samples of appropriate dimensions from both the pickled and tanned hides were cut and irradiated with artificial UV light for different time duration of 6-30 h. The irradiated samples were then analyzed using the DMA in the multi-frequency mode. It was found that irradiation caused an increase in the storage modulus (E 0 ) of pickled hide over the entire irradiation of 6 h followed by consistent decrease up to a duration of 30 h. Tanning caused an increase in tand that consistently decreased with the increase in the duration of irradiation. In addition, UV irradiation caused an increase in dynamic viscosity of pickled hide, but a decrease in tanned hide. The results show the predominant elastic nature of bovine hides as indicated by tand magnitudes less than a unit.

show abstract

“…It is proposed that this is due to the extra mechanical load placed on the tendons on the exercising animals (due to their higher activity levels) stimulating fibril thickening [28]. In bovine leather, fibril diameter is found to be only weakly correlated with strength [29]. …”

Section: Introductionmentioning

confidence: 99%

Age Dependent Differences in Collagen Alignment of Glutaraldehyde Fixed Bovine Pericardium

Sizeland

Wells

Higgins

et al. 2014

BioMed Research International

Self Cite

View full text Add to dashboard Cite

Bovine pericardium is used for heart valve leaflet replacement where the strength and thinness are critical properties. Pericardium from neonatal animals (4–7 days old) is advantageously thinner and is considered as an alternative to that from adult animals. Here, the structures of adult and neonatal bovine pericardium tissues fixed with glutaraldehyde are characterized by synchrotron-based small angle X-ray scattering (SAXS) and compared with the mechanical properties of these materials. Significant differences are observed between adult and neonatal tissue. The glutaraldehyde fixed neonatal tissue has a higher modulus of elasticity (83.7 MPa) than adult pericardium (33.5 MPa) and a higher normalised ultimate tensile strength (32.9 MPa) than adult pericardium (19.1 MPa). Measured edge on to the tissue, the collagen in neonatal pericardium is significantly more aligned (orientation index (OI) 0.78) than that in adult pericardium (OI 0.62). There is no difference in the fibril diameter between neonatal and adult pericardium. It is shown that high alignment in the plane of the tissue provides the mechanism for the increased strength of the neonatal material. The superior strength of neonatal compared with adult tissue supports the use of neonatal bovine pericardium in heterografts.

show abstract

Collagen Fibril Diameter and Leather Strength

Cited by 47 publications

References 43 publications

Poisson's ratio of collagen fibrils measured by small angle X-ray scattering of strained bovine pericardium

Poisson's ratio of collagen fibrils measured by small angle X-ray scattering of strained bovine pericardium

Influence of UV radiation on the viscoelastic properties and dynamic viscosity of bovine hide using dynamic mechanical analysis

Age Dependent Differences in Collagen Alignment of Glutaraldehyde Fixed Bovine Pericardium

Contact Info

Product

Resources

About