Collagen-Based Therapies for Accelerated Wound Healing

Abstract

Wound healing is a complex and dynamic process essential for maintaining tissue integrity and functionality. As a key component of the extracellular matrix (ECM), Collagen plays a crucial role in orchestrating this regenerative process. Acting as a vital fibrous protein, collagen serves as a dynamic conductor, coordinating tissue regeneration and repair. This chapter explores the application of collagen in accelerating the wound healing process, starting with the fundamental role of collagen in ECM remodeling. It discusses how collagen promotes wound healing through different types of scaffolds, micro/nanoparticles, synthetic peptides, and interactions with extracellular vesicles (EVs). The chapter also delves into the regulatory function of collagen in cellular processes and evaluates strategies to stimulate collagen synthesis. In conclusion, it provides an overview of upcoming advancements in the dynamic field of collagen-based therapies for wound treatment.