“…Of note, the prevalence of hematological disorders, such as impairments in platelet, white blood cell functions, hemoglobin levels, and coagulation/fibrinolytic activity, has progressively increased due to the toxic effects of existing drugs developed from obsolete animal models [26] , [38] . Accordingly, some first- and second-generation antipsychotic medications such as chlorpromazine (CPZ) and clozapine respectively, used in the treatment of different psychotic disorders such as schizophrenia and bipolar disorder, have been associated with several adverse effects, notably promoting hematological disorders [37] , [43] , [49] , [50] . Hematological perturbations including any changes in the normal functioning of blood cells, including alterations in their numbers, size, or function, have been linked to chemical exposure and long-term use of some drugs [14] , [22] , [31] .…”