Collaborative Efforts May Improve Chronic Non-Cancer Pain Management in Asia: Findings from a Ten-Country Regional Survey

Cheung, Chi Wai; Choo, Chee Yong; Kim, Yong-Chul; Lin, Feng Sheng; Moon, Sucbei; Osio-Salido, Evelyn; Pan, Shengfa; Singh, Vivek Ajit; Yoon, Seung-Hwan; Ward, Lois; Moon, Hanlim; Bhagat, Abhishek

doi:10.4172/2167-0846.1000225

Cited by 5 publications

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“…The ACHEON (Current practices of cancer and chronic non-cancer pain management: A Pan-Asian study) study is the first large-scale multinational survey conducted to evaluate the attitudes and perceptions of physicians and patients toward pain management across 10 Asian countries/regions. Findings from the surveys on cancer [18] and non-cancer pain patients [11] were previously reported. The results of the survey conducted in non-cancer pain patients demonstrated inadequate pain control in the participating countries/regions and several barriers to treatment optimization [11].…”

Section: Introductionmentioning

confidence: 78%

“…Findings from the surveys on cancer [18] and non-cancer pain patients [11] were previously reported. The results of the survey conducted in non-cancer pain patients demonstrated inadequate pain control in the participating countries/regions and several barriers to treatment optimization [11].…”

Section: Introductionmentioning

confidence: 78%

“…The design of the ACHEON study has been described previously [11]. Briefly, the ACHEON study was a cross-sectional survey conducted in 10 countries/regions in Asia: China, Hong Kong, Indonesia, the Republic of Korea, Malaysia, Philippines, Singapore, Taiwan, Thailand, and Vietnam.…”

Section: Survey Designmentioning

confidence: 99%

“…The design and conception of the questionnaire have been described previously [11]. Questions focused on the following aspects: patients' current pain levels, treatments prescribed for pain relief and their associated AEs, attitudes and behaviors toward treatment and employment status, and the effect of pain on their ADLs and work.…”

Section: Questionnairementioning

confidence: 99%

“…If left untreated, chronic pain can negatively affect patients' physical and emotional well-being, work productivity, and their quality of lives (QoL). These consequences impose a significant socioeconomic burden on patients, families, and society [6,7,11].…”

Section: Introductionmentioning

confidence: 99%

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Inadequate Management of Chronic Non-cancer Pain and Treatment-Related Adverse Events in Asia: Perspectives from Patients from 10 Countries/Regions

Cheung

Choo

Kim

et al. 2019

SN Compr. Clin. Med.

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Findings from the published ACHEON study revealed inadequate pain relief for chronic non-cancer pain (CNCP) across 10 Asian countries/regions. Hence, we performed additional analyses on the survey data to understand management practices for relieving CNCP and treatment-related adverse events (AEs). Descriptive statistics were used to summarize patients' profile, prescribed treatments, and associated AEs. Two-sample t test was used to compare pain levels between treatment groups. Univariate analyses were conducted to identify factors associated with pain intensity, presence of any common AEs, perceived treatment adequacy, patient-physician interaction, and employment status. Of 1305 patients surveyed, the median duration of CNCP was 24 (interquartile range, 39) months. The majority of patients (89.3%) reported having moderate (44.4%) or severe pain (44.9%). Most patients (80.1%) were prescribed non-opioids, while 16.2% of patients were untreated for pain. Although over half of the treated patients (53.8%) experienced AEs while receiving pain treatment, two-fifths were prescribed medications to manage these AEs. High pain levels, presence of AEs, and employment status influenced patients' perception of treatment adequacy. Patients were more willing to inform their physicians when pain levels were higher and when they perceived sufficient time with physicians. These findings revealed inadequate treatment of CNCP in patients from the participating countries/regions. CNCP management may be improved through increased physician-patient interaction time and adopting a biopsychosocial model for treatment. A proactive and multidimensional approach is required to manage CNCP and potential treatment-related AEs so as to provide optimal care for patients experiencing CNCP.

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Section: Introductionmentioning

confidence: 78%

Section: Introductionmentioning

confidence: 78%

Section: Survey Designmentioning

confidence: 99%

Section: Questionnairementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Inadequate Management of Chronic Non-cancer Pain and Treatment-Related Adverse Events in Asia: Perspectives from Patients from 10 Countries/Regions

Cheung

Choo

Kim

et al. 2019

SN Compr. Clin. Med.

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Prolonged-Release (PR) Oxycodone/Naloxone Improves Bowel Function Compared with Oxycodone PR and Provides Effective Analgesia in Chinese Patients with Non-malignant Pain: A Randomized, Double-Blind Trial

et al. 2020

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Introduction: Prolonged-release oxycodone/ naloxone (OXN PR), combining an opioid analgesic with selective blockade of enteric lopioid receptors, provided effective analgesia and improved bowel function in patients with moderate-to-severe pain and opioid-induced constipation in clinical trials predominantly conducted in Western countries. This doubleblind randomized controlled trial investigated OXN PR (N = 116) versus prolonged-release oxycodone (OXY PR, N = 115) for 8 weeks at doses up to 50 mg/day in patients with moderate-to-severe, chronic, non-malignant musculoskeletal pain and opioid-induced constipation recruited in China. Methods: A total of 234 patients at least 18 years of age with non-malignant musculoskeletal pain for more than 4 weeks that was moderate-to-severe in intensity and required round-the-clock opioid therapy were randomized (1:1) to OXN PR or OXY PR. The primary endpoint was bowel function using the Bowel Enhanced Digital Features To view enhanced digital features for this article go to https://doi.org/10.6084/ m9.figshare.11663295.

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Cancer Pain Management in French-Speaking African Countries: Assessment of the Current Situation and Research Into Factors Limiting Treatment and Access to Analgesic Drugs

Hadjiat

Perrot

2022

Front. Public Health

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IntroductionThere is a dearth of research on the incidence and treatment of cancer pain in Africa. Yet Africa, with other developing countries, accounts for more than half of all cancer diagnoses, and it is estimated that cancer incidence in Africa will double by 2030.ObjectivesThis research protocol outlines an approach to investigate cancer pain in French-speaking African countries. The protocol intends to determine and describe the treatment and management of cancer pain in these countries. Barriers to treating cancer pain will be explored and the results will be collated to make a series of recommendations on policy positions, regulatory frameworks and protocols.MethodsA mixed-methods, co-creation methodology has been selected to ensure the societal impact of the research outcomes. This research will use both qualitative and quantitative data collection methods and analyses. The research will begin with a review of the policies and legislation that exist in relation to cancer pain management and the use of analgesics, in each French-speaking African country. An Experts Steering Committee will then be created to provide guidance on the protocol and research design and access to participants, as well as to execute on the administration of surveys to local structures and international experts. A series of semi-structured, qualitative interviews with experts and clinicians in the field of screening and management of cancer pain and access to treatment will follow. Purposive and snowball sampling will be used to select the respondent experts. The semi-structured interviews will be conducted to determine the main trends and barriers to the treatment of cancer pain in French-speaking African countries. From this qualitative research, two surveys will be developed and then administered: one to validate the policy and regulatory context, and the other to determine experts and healthcare professionals experience and perceptions of cancer pain.Results/ConclusionsThe results will be analyzed using quantitative and qualitative methods to determine themes and perceptions of cancer pain and treatment, from the policy level to the healthcare professional level. Evaluation of the results will lead to recommendations for a comprehensive framework for cancer pain treatment in French-speaking Africa.

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Collaborative Efforts May Improve Chronic Non-Cancer Pain Management in Asia: Findings from a Ten-Country Regional Survey

Cited by 5 publications

References 0 publications

Inadequate Management of Chronic Non-cancer Pain and Treatment-Related Adverse Events in Asia: Perspectives from Patients from 10 Countries/Regions

Inadequate Management of Chronic Non-cancer Pain and Treatment-Related Adverse Events in Asia: Perspectives from Patients from 10 Countries/Regions

Prolonged-Release (PR) Oxycodone/Naloxone Improves Bowel Function Compared with Oxycodone PR and Provides Effective Analgesia in Chinese Patients with Non-malignant Pain: A Randomized, Double-Blind Trial

Cancer Pain Management in French-Speaking African Countries: Assessment of the Current Situation and Research Into Factors Limiting Treatment and Access to Analgesic Drugs

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