Collaboration with an infection control team promoted appropriate antibiotic use for third molar extraction at a Japanese hospital

Yoshida, Hisato; Matsuda, Shinpei; Aratani, Tomonori; Tsukamoto, Hitoshi; Yoshimura, Hitoshi; Sano, Kazuo; Iwasaki, Hiromichi

doi:10.1016/j.jiac.2020.01.003

Cited by 10 publications

(10 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, there are reports in the literature that show the opposite (Yoshida et al, 2020), reports a significant reduction in the rate of infection at the surgical site after the removal of third molars with the use of antibiotic therapy. The author also notes that the infection rate was even higher in patients who received 3rd generation cephalosporin administered orally when compared to patients who received penicillin.…”

Section: Discussionmentioning

confidence: 98%

Effect of antibiotic therapy in the postoperative period of third molar surgeries: a split-mouth, randomized and controlled study

Oliveira

Botture

Sato

et al. 2022

RSD

View full text Add to dashboard Cite

Purpose: The objective of this randomized clinical trial was to evaluate the postoperative period of 32 third molars, semi-included or included, in a split mouth, of patients from the São Paulo State University. Material and Methods: The teeth were divided into two groups, in the test group drug treatment with Amoxicillin 500 mg, Dexamethasone 4 mg and Dipyrone 500 mg and in the control group patients received treatment with Dexamethasone 4 mg and Dipyrone 500 mg. The parameters used were edema, trismus and pain, measured before and after the operation, where the benefits of antibiotic therapy were evaluated. To compare the data, an analog pain scale was used, the method of Ustün, and the millimeter ruler, being submitted to Student's T test. Results: Both test and control groups had similar values, with no statistically significant difference in the incidence of postoperative complications, as well as in the presence of edema, pain and more pronounced trismus between the groups analyzed in the study. Conclusions: In view of the statistical results obtained, it was not possible to state that the use of antibiotic therapy was beneficial when related to edema, trismus and pain.

show abstract

Section: Discussionmentioning

confidence: 98%

Effect of antibiotic therapy in the postoperative period of third molar surgeries: a split-mouth, randomized and controlled study

Oliveira

Botture

Sato

et al. 2022

RSD

View full text Add to dashboard Cite

show abstract

“…19 Similarly, a retrospective study showed that the same dose of AMPC was effective in Japanese patients. 5 These Japanese articles and the aforementioned systematic reviews and meta-analyses differ in target patients; however, these articles targeted Japanese patients, the aforementioned systematic reviews and meta-analyses targeted Caucasians. Thus, this difference in effectiveness may suggest that the antimicrobial effects of AMPC are associated with background factors of the patients.…”

Section: Discussionmentioning

confidence: 99%

“…A retrospective cohort study reported that the incidence rate of SSI after impacted third molar (ITM) surgery in patients who received third-generation oral cephalosporins (8.8%) was higher than that of AMPC (0.5%). 5 Another retrospective study reported that oral thirdgeneration cephalosporins decreased from 70.4 to 0.3%, whereas AMPC increased from 0% to 98%. However, the incidence rate of SSI did not change over the study period, with an average total incidence of 3.5%.…”

Section: What Is K Nown and Objec Tivementioning

confidence: 99%

“…Following the declaration of the “National Action Plan on AMR,” several studies have addressed reductions in the use of third‐generation oral cephalosporins and increases in the use of AMPC and evaluated clinical outcomes in dentistry at our facilities. A retrospective cohort study reported that the incidence rate of SSI after impacted third molar (ITM) surgery in patients who received third‐generation oral cephalosporins (8.8%) was higher than that of AMPC (0.5%) 5 . Another retrospective study reported that oral third‐generation cephalosporins decreased from 70.4 to 0.3%, whereas AMPC increased from 0% to 98%.…”

Section: What Is Known and Objectivementioning

confidence: 99%

See 1 more Smart Citation

Evaluation of the strategies to reduce third‐generation oral cephalosporins in dentistry at a Japanese academic hospital: An interrupted time series analysis

Yamagami

Narumi

Saito

et al. 2022

Clinical Pharmacy Therapeu

View full text Add to dashboard Cite

What is known and objective: Third-generation oral cephalosporins, especially cefcapene-pivoxil (CFPN-PI), have been used frequently in the Japanese dental field.In December 2014 and April 2016, the newly published clinical guidelines recommended the use of amoxicillin (AMPC). Thus, it is important to evaluate the impact of these guidelines on the prescription profiles of prophylactic antibiotics, clinical outcomes and cost-effectiveness of antibiotics. Methods:We conducted a retrospective study to analyse an interrupted time series analysis from April 2013 to March 2020 at the Department of Dentistry of Hokkaido University Hospital. A segmented regression model was used to estimate the changes in the incidence of infectious complications following tooth extraction. Prescribed antibiotic data were evaluated via days of therapy (DOT). Antibiotic costs were calculated in terms of the Japanese yen (JPY). Results and Discussion:We identified 17,825 eligible patients. The incidence rates of infectious complications (SSI + dry socket) and SSI after tooth extraction were 3.2% and 2.2%, respectively, during the entire period. The extraction of impacted third molars corresponded to 5.0% and 3.4%, respectively. However, their incidence rates were not significantly different during this period. The use of prophylactic antibiotics and antibiotic cost showed consistent trends following the implementation of guidelines. The mean DOT of CFPN-PI decreased (ranging from 4893.6 DOTs/1000

show abstract

“…9,10 Therefore, candidates for the infection control team were selected from those who displayed a sense of responsibility, strong professional ability, great management potential, good psychological and It was important to build an infection control team management collaboration mechanism, which recognizes that personal development is inseparable from teamwork, in-depth practice and research, and the cultivation of innovative thinking. 11,12 Therefore, it has been essential to allow each team member to pursue their own professional development while gaining a basic knowledge of infection control in combination with exercising basic management skills, in a way that fosters collaboration between doctors and nurses. In so doing, the hospital has been successful in building a unified infection control management system.…”

Section: Discussionmentioning

confidence: 99%

The Use of a Three-in-One Practice-Management-Innovation Training Model in the Construction of an Infection Control Team

Min

Yang

Gong

2021

RMHP

View full text Add to dashboard Cite

Objective: This study aims to explore the role of a three-in-one practice, management, and innovation training model (also called as three-in-one practice-management-innovation training model) in the construction of an infection control team. Methods: This study retrospectively analyzed the position structure, mastery of professional knowledge, and working methods of the full-time and part-time personnel of the Changzhou Cancer Hospital, compared the training content of Jiangsu Hospital Infection Control Center with the actual situation of the hospital, and formulated and implemented a three-in-one practicemanagement-innovation training model. First, the team members were selected for the construction and management of the Hospital Infection Management Department according to the relevant responsibility and management requirements, and their learning and mastery of the basic knowledge and skills concerning infection control were completed based on their professional roles. In line with the regulations of the hospital and department, full-time personnel were ensured of having the opportunity to participate in provincial-and municipal-level academic exchanges and then learn from each other, through collaboration between doctors and nurses, how to exercise basic management skills. At the same time, a fair competitive incentive mechanism was established through the three-level network of the hospital infection committee, the hospital infection management department, and nosocomial infection management department to implement innovative projectbased management and cultivate an awareness of hospital infection control in all employees. Results: The professional structure of the full-time infection control personnel has been optimized, the awareness of the infection control team concerning active participation in practice has gradually increased, and infection control management and innovation has been significantly improved. Conclusion:After the selection of an infection control management team and the delivery of well-planned training, the quality of infection control management has improved.

show abstract

Collaboration with an infection control team promoted appropriate antibiotic use for third molar extraction at a Japanese hospital

Cited by 10 publications

References 17 publications

Effect of antibiotic therapy in the postoperative period of third molar surgeries: a split-mouth, randomized and controlled study

Effect of antibiotic therapy in the postoperative period of third molar surgeries: a split-mouth, randomized and controlled study

Evaluation of the strategies to reduce third‐generation oral cephalosporins in dentistry at a Japanese academic hospital: An interrupted time series analysis

The Use of a Three-in-One Practice-Management-Innovation Training Model in the Construction of an Infection Control Team

Contact Info

Product

Resources

About